CREB3L1 and UBA1

Number of citations of the paper that reports this interaction (PMID 8051045)
1

Data Source:
BioGRID (enzymatic study)

		CREB3L1	UBA1
Gene Name		cAMP responsive element binding protein 3-like 1	ubiquitin-like modifier activating enzyme 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Heterochromatin Nucleus Cytoplasm Mitochondrion Lysosomal Membrane Cytosol Endosome Membrane Desmosome Rough Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding CAMP Response Element Binding Sequence-specific DNA Binding	Ubiquitin Activating Enzyme Activity Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Bone Mineralization Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter	Cellular Response To DNA Damage Stimulus Protein Ubiquitination Modification-dependent Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: C5 CREB3 CREB3L3 CREM DDIT3 FAM3C FBXW7 FXYD6 GPR25 JAGN1 MFSD5 NRM PGRMC1 PRKAB2 RUNX1T1 SLC30A8 SLC35B4 TMEM147 TMEM218 TMEM234 TSPO UBA1 UBE2D3	39 interactors: BUB3 CDC34 CDK1 CREB3L1 CREB3L2 ECHS1 GAN GRB2 HGS HSPH1 MGMT PIAS3 SEMA3F SMAD5 TAF9 TMCC2 TSSC4 TTC19 UBC UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2H UBE2J1 UBE2K UBE2L3 UBE2R2 UBE2S UBE2T UBE2W UBTD2
Entrez ID		90993	7317
HPRD ID		16751	02440
Ensembl ID		ENSG00000157613	ENSG00000130985
Uniprot IDs		B2RA75 Q96BA8	P22314
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Response To Organic Substance ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Response To Stress Response To Unfolded Protein Regulation Of Lipid Biosynthetic Process Regulation Of Ion Homeostasis Response To Endoplasmic Reticulum Stress Ion Transport Negative Regulation Of Cell Cycle Signaling Cellular Response To Organic Substance Negative Regulation Of Biosynthetic Process Cell Communication Modification-dependent Protein Catabolic Process Regulation Of Cytokine Production Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Negative Regulation Of SREBP Signaling Pathway Granulocyte Colony-stimulating Factor Signaling Pathway UDP-xylose Transport Molybdate Ion Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Protein Catabolic Process Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Signal Transduction Proteasomal Protein Catabolic Process Inorganic Anion Transport Protein Catabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Macrophage Chemotaxis UDP-N-acetylglucosamine Transport Release From Viral Latency Regulation Of Transcription Involved In Anterior/posterior Axis Specification UDP-N-acetylglucosamine Transmembrane Transport Regulation Of Lipid Metabolic Process Positive Regulation Of Neuron Death Anion Transport Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Neutrophil Differentiation Response To Vitamin B1	Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K11-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Modification Process Proteolysis Catabolic Process Cellular Protein Metabolic Process Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Protein K63-linked Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Protein Monoubiquitination Cellular Response To Stress Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Protein Ubiquitination Cellular Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Response To Organic Substance Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Toll-like Receptor 3 Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Mitotic Cell Cycle Checkpoint Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cell Cycle Process Mitotic Spindle Assembly Checkpoint Negative Regulation Of Chromosome Organization Spindle Assembly Checkpoint
Tagcloud ?		aggressive bladder candidate clearly colony downregulation hence highlights htra3 hypermethylation immunohistochemical interestingly invasive j82 mediates nuclei potentially predominately proposed public putative pyrosequencing set suppression suppressor tgf tissues verified	aspect bax box caspases consisting counterpart debcl degrading documented drosophila e3 fruitfly homologue iaps identifies involve ligase modifier multimeric proteasome proteolytic regulators scf screen shed slimb stimulates trcp ubiquitin
Tagcloud (Difference) ?		aggressive bladder candidate clearly colony downregulation hence highlights htra3 hypermethylation immunohistochemical interestingly invasive j82 mediates nuclei potentially predominately proposed public putative pyrosequencing set suppression suppressor tgf tissues verified	aspect bax box caspases consisting counterpart debcl degrading documented drosophila e3 fruitfly homologue iaps identifies involve ligase modifier multimeric proteasome proteolytic regulators scf screen shed slimb stimulates trcp ubiquitin
Tagcloud (Intersection) ?