CREB3L1 and SLC30A8

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CREB3L1	SLC30A8
Gene Name		cAMP responsive element binding protein 3-like 1	solute carrier family 30 (zinc transporter), member 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Golgi Apparatus Plasma Membrane Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle Secretory Granule Transport Vesicle Membrane Secretory Granule Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding CAMP Response Element Binding Sequence-specific DNA Binding	Zinc Ion Transmembrane Transporter Activity Zinc Ion Binding Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Bone Mineralization Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Transcription From RNA Polymerase II Promoter	Zinc Ion Transport Cellular Zinc Ion Homeostasis Response To Glucose Insulin Secretion Positive Regulation Of Insulin Secretion Sequestering Of Zinc Ion Response To Interferon-gamma Glucose Homeostasis Cellular Protein Metabolic Process Transmembrane Transport Regulation Of Vesicle-mediated Transport Regulation Of Sequestering Of Zinc Ion Response To Interleukin-1 Zinc Ion Transmembrane Transport
Pathways			Metal ion SLC transporters Peptide hormone metabolism Zinc efflux and compartmentalization by the SLC30 family Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Insulin processing Zinc transporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS			Asthma ( 21814517) Fasting glucose-related traits ( 20081858) Fasting glucose-related traits (interaction with BMI) ( 22581228) Glycated hemoglobin levels ( 19096518) Obesity-related traits ( 23251661) Proinsulin levels ( 21873549) Type 2 diabetes ( 17293876 22693455 20581827 19401414 17463246 17463248 17463249 17460697 19056611) Type 2 diabetes and other traits ( 19734900)
Protein-Protein Interactions		23 interactors: C5 CREB3 CREB3L3 CREM DDIT3 FAM3C FBXW7 FXYD6 GPR25 JAGN1 MFSD5 NRM PGRMC1 PRKAB2 RUNX1T1 SLC30A8 SLC35B4 TMEM147 TMEM218 TMEM234 TSPO UBA1 UBE2D3	1 interactors: CREB3L1
Entrez ID		90993	169026
HPRD ID		16751	15370
Ensembl ID		ENSG00000157613	ENSG00000164756
Uniprot IDs		B2RA75 Q96BA8	Q8IWU4
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein Response To Organic Substance ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Response To Stress Response To Unfolded Protein Regulation Of Lipid Biosynthetic Process Regulation Of Ion Homeostasis Response To Endoplasmic Reticulum Stress Ion Transport Negative Regulation Of Cell Cycle Signaling Cellular Response To Organic Substance Negative Regulation Of Biosynthetic Process Cell Communication Modification-dependent Protein Catabolic Process Regulation Of Cytokine Production Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Negative Regulation Of SREBP Signaling Pathway Granulocyte Colony-stimulating Factor Signaling Pathway UDP-xylose Transport Molybdate Ion Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Protein Catabolic Process Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Neuron Apoptotic Process Signal Transduction Proteasomal Protein Catabolic Process Inorganic Anion Transport Protein Catabolic Process Negative Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Macrophage Chemotaxis UDP-N-acetylglucosamine Transport Release From Viral Latency Regulation Of Transcription Involved In Anterior/posterior Axis Specification UDP-N-acetylglucosamine Transmembrane Transport Regulation Of Lipid Metabolic Process Positive Regulation Of Neuron Death Anion Transport Cellular Response To Stimulus Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Neutrophil Differentiation Response To Vitamin B1
Tagcloud ?		aggressive bladder candidate clearly colony downregulation hence highlights htra3 hypermethylation immunohistochemical interestingly invasive j82 mediates nuclei potentially predominately proposed public putative pyrosequencing set suppression suppressor tgf tissues verified
Tagcloud (Difference) ?		aggressive bladder candidate clearly colony downregulation hence highlights htra3 hypermethylation immunohistochemical interestingly invasive j82 mediates nuclei potentially predominately proposed public putative pyrosequencing set suppression suppressor tgf tissues verified
Tagcloud (Intersection) ?