CLIC3 and EFHC2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLIC3	EFHC2
Gene Name		chloride intracellular channel 3	EF-hand domain (C-terminal) containing 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Chloride Channel Complex Extracellular Vesicular Exosome
	Molecular Function	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding	Calcium Ion Binding
	Biological Process	Chloride Transport Signal Transduction Regulation Of Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP DNM1 EFHC2 MAPK15 POT1	30 interactors: ARHGEF5 ARMC7 CCDC120 CCHCR1 CCNG2 CLIC3 COPE CYFIP1 DGCR6 EDC3 EGLN3 EMD EXOC8 JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 PBLD PLOD3 PTK6 RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		9022	80258
HPRD ID		05941	06540
Ensembl ID
Uniprot IDs		O95833	Q5JST6
PDB IDs		3FY7 3KJY	2Z13 2Z14
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Replication Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Strand Elongation Regulation Of DNA Replication Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Telomere Formation Via Telomerase Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Positive Regulation Of Helicase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Neuron Remodeling Axon Guidance Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Negative Regulation Of Cellular Metabolic Process Axonogenesis Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Axon Development Cell Morphogenesis Involved In Neuron Differentiation RNA-dependent DNA Replication Chemotaxis Copper Ion Homeostasis Suckling Behavior Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Projection Morphogenesis Endocytosis Positive Regulation Of Cellular Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Telomere Maintenance Via Telomere Lengthening Endosome Organization Cell Morphogenesis Involved In Differentiation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation	Regulation Of Podosome Assembly
Tagcloud ?		acini acquire alpha5beta1 basement cargo com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts rab25 recycling trafficking transferred
Tagcloud (Difference) ?		acini acquire alpha5beta1 basement cargo com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts rab25 recycling trafficking transferred
Tagcloud (Intersection) ?