TAF1B and TRB

Number of citations of the paper that reports this interaction (PubMedID 12511607)
0

Data Source:
BioGRID (pull down)

		TAF1B	TRB
Description		TATA-box binding protein associated factor, RNA polymerase I subunit B	T cell receptor beta locus
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus RNA Polymerase I Core Factor Complex	Plasma Membrane Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding Zinc Ion Binding TBP-class Protein Binding Metal Ion Binding	Signaling Receptor Activity
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly DNA-templated Transcription Transcription By RNA Polymerase I Nucleolar Large RRNA Transcription By RNA Polymerase I	Detection Of Tumor Cell Immune System Process T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cell Surface Receptor Signaling Pathway
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Egg allergy (maternal genetic effects) ( 29489655) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Nonsyndromic cleft lip with cleft palate ( 28232668) Prostate cancer ( 23535732)	Narcolepsy ( 24204295)
Interacting Genes		26 interacting genes: ACADVL APP CALR EP300 ESR1 H2AC20 H2BC21 H3C1 H4C1 MEOX2 MYC NAPB NEDD4 NEDD4L PGR RRN3 RXRA SRPK1 TAF1A TAF1C TBP THAP7 TP53 TRB TRIM24 UBTF	14 interacting genes: CD1D CD247 CD3D CD3E CD3G CTCF HLA-A HLA-B HLA-DRB1 NCOA6 TAF1B TRA TRAT1 TRD
Entrez ID		9014	6957
HPRD ID		05363	01739
Ensembl ID		ENSG00000115750
Uniprot IDs		Q53T94
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Binding DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Protein-containing Complex Organization Transcription By RNA Polymerase II Protein-DNA Complex Assembly RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Chromatin Organization Nucleoplasm Protein-containing Complex Assembly Chromatin RNA Polymerase Transcription Factor SL1 Complex RNA Polymerase I General Transcription Initiation Factor Activity RNA Metabolic Process Transcription Preinitiation Complex Assembly Macromolecule Biosynthetic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Protein-containing Complex Transcription Initiation At RNA Polymerase I Promoter Nucleus Chromatin Remodeling Nuclear Receptor-mediated Signaling Pathway Transcription Coregulator Binding Estrogen Response Element Binding Transcription Coactivator Binding Regulation Of Signal Transduction By P53 Class Mediator Transcription By RNA Polymerase I Enzyme Binding Euchromatin Core Promoter Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hormone-mediated Signaling Pathway Nucleic Acid Metabolic Process Cellular Component Assembly Epigenetic Regulation Of Gene Expression Nuclear Steroid Receptor Activity Regulation Of MiRNA Transcription DNA-templated Transcription Initiation Positive Regulation Of RNA Metabolic Process Chromosome Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation Structural Constituent Of Chromatin Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To UV Regulation Of MiRNA Metabolic Process	Alpha-beta T Cell Receptor Complex Adaptive Immune Response T Cell Receptor Complex Detection Of Biotic Stimulus Detection Of Bacterium T Cell Receptor Binding T Cell Receptor Signaling Pathway Positive Regulation Of Immune Response Gamma-delta T Cell Receptor Complex Antigen Receptor-mediated Signaling Pathway Immune Response External Side Of Plasma Membrane Antigen Processing And Presentation Of Endogenous Antigen T Cell Selection Regulation Of Immune Response Alpha-beta T Cell Activation Positive Regulation Of Immune System Process Positive Regulation Of T Cell Mediated Cytotoxicity Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Mediated Cytotoxicity Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Thymic T Cell Selection Immune System Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive T Cell Selection Immune Response-activating Signaling Pathway Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Immune Response-regulating Signaling Pathway Gamma-delta T Cell Activation Activation Of Immune Response Thymic T Cell Selection Regulation Of Immune System Process Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Detection Of Stimulus Regulation Of T Cell Mediated Immunity Lumenal Side Of Endoplasmic Reticulum Membrane TAP Binding T Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains T Cell Activation Peptide Antigen Binding Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Exogenous Antigen Protection From Natural Killer Cell Mediated Cytotoxicity Response To Bacterium Regulation Of T Cell Proliferation Immune Response To Tumor Cell
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