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TAF1B and UBTF
Number of citations of the paper that reports this interaction (PMID
10913176
)
53
Data Source:
BioGRID
(pull down)
TAF1B
UBTF
Gene Name
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
upstream binding transcription factor, RNA polymerase I
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Extracellular Vesicular Exosome
RNA Polymerase I Core Factor Complex
Nucleoplasm
Nucleolus
Molecular Function
RNA Polymerase I CORE Element Sequence-specific DNA Binding
RNA Polymerase I CORE Element Sequence-specific DNA Binding Transcription Factor Recruiting Transcription Factor Activity
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
TBP-class Protein Binding
Metal Ion Binding
DNA Binding
Chromatin Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Chromatin Silencing At RDNA
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Transcription, DNA-templated
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Gene Expression
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Chromatin Remodeling
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Gene Expression
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription From RNA Polymerase I Promoter
Pathways
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
SIRT1 negatively regulates rRNA Expression
Negative epigenetic regulation of rRNA expression
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Protein-Protein Interactions
24 interactors:
APP
EP300
ESR1
HIST1H3A
HIST1H4A
HIST2H2AC
HIST2H2BE
MYC
NAPB
NEDD4
NEDD4L
PGR
RRN3
RXRA
SRPK1
TAF1A
TAF1C
TAF1D
TBP
THAP7
TP53
TRB
TRIM24
UBTF
31 interactors:
CCNA2
CCND1
CCNE1
CD3EAP
CDK2
CDK4
CENPC
CHGB
CREBBP
CSNK2A1
IRS1
IRS2
LEF1
MAD1L1
MAPK1
MAPK3
MDM2
POLR1E
RB1
RBL2
RUNX2
SERPINH1
SMURF1
TAF1
TAF1A
TAF1B
TAF1C
TAF1D
TBP
TCOF1
ZMYM2
Entrez ID
9014
7343
HPRD ID
05363
02814
Ensembl ID
ENSG00000115750
ENSG00000108312
Uniprot IDs
Q53T94
P17480
PDB IDs
1K99
1L8Y
1L8Z
2HDZ
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Gene Expression
DNA-templated Transcription, Initiation
Chromatin Silencing At RDNA
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Transcription Initiation From RNA Polymerase I Promoter
Negative Regulation Of RNA Biosynthetic Process
Transcription From RNA Polymerase I Promoter
Negative Regulation Of Gene Expression, Epigenetic
Gene Expression
Chromatin Silencing
Negative Regulation Of Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Termination Of RNA Polymerase I Transcription
Negative Regulation Of Cellular Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Transcription Elongation From RNA Polymerase I Promoter
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Silencing
Regulation Of Gene Expression, Epigenetic
Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
DNA-templated Transcription, Termination
Positive Regulation Of Transcription, DNA-templated
Chromatin Organization
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Elongation
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Macromolecule Biosynthetic Process
Chromosome Organization
Viral Process
DNA Packaging
Intracellular Receptor Signaling Pathway
Positive Regulation Of Metabolic Process
Biosynthetic Process
DNA Conformation Change
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
DNA-templated Transcription, Initiation
DNA-templated Transcription, Elongation
Regulation Of Gene Expression
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
Chromatin Silencing At RDNA
Cellular Macromolecule Biosynthetic Process
Gene Expression
Regulation Of Mitotic Cell Cycle Phase Transition
Cell Cycle
Regulation Of Cell Cycle Phase Transition
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Chromatin Silencing
Regulation Of RNA Biosynthetic Process
Mitotic Cell Cycle
Positive Regulation Of Macromolecule Biosynthetic Process
Mitotic Cell Cycle Checkpoint
Regulation Of RNA Metabolic Process
Cell Division
Positive Regulation Of Cellular Biosynthetic Process
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Negative Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cell Proliferation
Regulation Of Cell Cycle Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Mitotic Cell Cycle Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cell Cycle Checkpoint
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Gene Expression
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
RRNA Transcription
Tagcloud
?
analysed
blocking
c8
coding
crc
frameshift
gc
harboured
heterogeneity
instability
intratumoural
ith
microsatellite
mononucleotide
msi
mss
mutational
regional
ribosomal
rrna
somatic
strand
summary
taf1a
taf1c
tata
tbp
tumourigenesis
ubf
Tagcloud (Difference)
?
analysed
blocking
c8
coding
crc
frameshift
gc
harboured
heterogeneity
instability
intratumoural
ith
microsatellite
mononucleotide
msi
mss
mutational
regional
ribosomal
rrna
somatic
strand
summary
taf1a
taf1c
tata
tbp
tumourigenesis
ubf
Tagcloud (Intersection)
?