TRB and CD3D

Number of citations of the paper that reports this interaction (PMID 2138083)
29

Data Source:
HPRD (in vivo)

		TRB	CD3D
Gene Name		T cell receptor beta locus	CD3d molecule, delta (CD3-TCR complex)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Plasma Membrane Integral Component Of Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex
	Molecular Function		Transcription Coactivator Activity Transmembrane Signaling Receptor Activity Protein Heterodimerization Activity
	Biological Process		Cell Surface Receptor Signaling Pathway T Cell Differentiation T Cell Costimulation Positive Thymic T Cell Selection Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Immune Response T Cell Receptor Signaling Pathway
Pathways			TCR signaling Downstream TCR signaling Generation of second messenger molecules Translocation of ZAP-70 to Immunological synapse Costimulation by the CD28 family PD-1 signaling Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Phosphorylation of CD3 and TCR zeta chains Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CD1D CD247 CD3D CD3E CD3G CTCF HLA-A HLA-B HLA-DRB1 NCOA6 NCOR1 TAF1B TRA TRAT1 TRD	11 interactors: AP2M1 CANX CD247 CD3E CD3G CD8A CD8B HERPUD1 KCNA3 TRA TRB
Entrez ID		6957	915
HPRD ID		01739	01730
Ensembl ID			ENSG00000167286
Uniprot IDs			B0YIY4 P04234
PDB IDs			1XIW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion T Cell Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Regulation Of Immune Response Regulation Of T Cell Activation Positive Regulation Of Cell Activation Positive Regulation Of Immune System Process Detection Of Bacterium T Cell Costimulation Immune System Process Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Detection Of Biotic Stimulus Regulation Of Cell Activation Regulation Of Immune System Process Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Of Endogenous Antigen Innate Immune Response Immune Response-regulating Signaling Pathway T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Protection From Natural Killer Cell Mediated Cytotoxicity T Cell Differentiation Immune Response T Cell Selection Lymphocyte Activation Defense Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Leukocyte Activation Cell Surface Receptor Signaling Pathway Single Organismal Cell-cell Adhesion Antigen Processing And Presentation Lymphocyte Differentiation Interferon-gamma-mediated Signaling Pathway Regulation Of T Cell Anergy Regulation Of Interferon-gamma Production Hemopoiesis Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Cellular Response To Interferon-gamma	Regulation Of Defense Response To Virus By Virus Immune System Process Regulation Of Immune System Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Signaling T Cell Costimulation Cell Communication Regulation Of Defense Response To Virus Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Regulation Of Immune Response T Cell Receptor Signaling Pathway Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Leukocyte Activation Single Organismal Cell-cell Adhesion Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Endocytosis Clathrin-mediated Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Positive Regulation Of Cell-cell Adhesion Regulation Of Calcium-mediated Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Antigen Processing And Presentation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Cell Surface Receptor Signaling Pathway Regulation Of Lymphocyte Activation Cytotoxic T Cell Differentiation Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Signal Transduction Cell Adhesion Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Immune Response Viral Process Synaptic Transmission
Tagcloud ?		cdr3 clonotypes complementarity detailed effusion expansive extrapulmonary families firstly illumina manifestation mononuclear oligoclonal pbmcs peaks pemcs platform pleural pltb profiled repertoire sequenced skewed spectratyping tcr throughput trbj1 trbv trbv20	aurkb bub1b ccnb1 cd247 cd3g cd8a cdc20 cdca8 cenpa cytoscape dihydroxyfluorane epstain generank hindering itgb5 itk kif2c lcp2 limma lymphoblasts mad2l1 nup37 pik3r3 plcg2 prkcq rpa3 softwares vav3 zap70
Tagcloud (Difference) ?		cdr3 clonotypes complementarity detailed effusion expansive extrapulmonary families firstly illumina manifestation mononuclear oligoclonal pbmcs peaks pemcs platform pleural pltb profiled repertoire sequenced skewed spectratyping tcr throughput trbj1 trbv trbv20	aurkb bub1b ccnb1 cd247 cd3g cd8a cdc20 cdca8 cenpa cytoscape dihydroxyfluorane epstain generank hindering itgb5 itk kif2c lcp2 limma lymphoblasts mad2l1 nup37 pik3r3 plcg2 prkcq rpa3 softwares vav3 zap70
Tagcloud (Intersection) ?