TAF1B and RRN3

Number of citations of the paper that reports this interaction (PubMedID 11250903)
41

Data Source:
HPRD (in vivo, in vitro)

		TAF1B	RRN3
Description		TATA-box binding protein associated factor, RNA polymerase I subunit B	RNA polymerase I transcription factor RRN3
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase I Transcription Regulator Complex Nucleus Nucleoplasm RNA Polymerase Transcription Factor SL1 Complex Nucleolus RNA Polymerase I Core Factor Complex	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding Zinc Ion Binding TBP-class Protein Binding Metal Ion Binding	RNA Polymerase I Core Binding RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity Protein Binding RNA Polymerase Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly DNA-templated Transcription Transcription By RNA Polymerase I Nucleolar Large RRNA Transcription By RNA Polymerase I	RNA Polymerase I Preinitiation Complex Assembly In Utero Embryonic Development DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase I Promoter Nucleolus Organization Cytoplasm Organization Ribosome Biogenesis Positive Regulation Of DNA-templated Transcription Fibroblast Proliferation Homeostasis Of Number Of Cells Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA-templated Transcription Initiation
Pathways		SIRT1 negatively regulates rRNA expression NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape
Drugs
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Dental caries (decayed, missing and filled tooth surfaces) ( 31533690) Egg allergy (maternal genetic effects) ( 29489655) Non-response to selective serotonin reuptake inhibitors and depression ( 27622933) Nonsyndromic cleft lip with cleft palate ( 28232668) Prostate cancer ( 23535732)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Fruit consumption ( 32066663) Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311) Serum metabolite levels ( 33031748) Triglyceride levels ( 32154731)
Interacting Genes		26 interacting genes: ACADVL APP CALR EP300 ESR1 H2AC20 H2BC21 H3C1 H4C1 MEOX2 MYC NAPB NEDD4 NEDD4L PGR RRN3 RXRA SRPK1 TAF1A TAF1C TBP THAP7 TP53 TRB TRIM24 UBTF	10 interacting genes: CCNE1 CDK2 EIF3L MYO1C POLR1A POLR1B PPP2R2A TAF1A TAF1B TAF1C
Entrez ID		9014	54700
HPRD ID		05363	12004
Ensembl ID		ENSG00000115750	ENSG00000085721
Uniprot IDs		Q53T94	B7ZB55 F5H148 Q9NYV6
PDB IDs			7OBA
Enriched GO Terms of Interacting Partners?		DNA Binding DNA-templated Transcription Nucleobase-containing Compound Biosynthetic Process Protein-containing Complex Organization Transcription By RNA Polymerase II Protein-DNA Complex Assembly RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly Chromatin Organization Nucleoplasm Protein-containing Complex Assembly Chromatin RNA Polymerase Transcription Factor SL1 Complex RNA Polymerase I General Transcription Initiation Factor Activity RNA Metabolic Process Transcription Preinitiation Complex Assembly Macromolecule Biosynthetic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Protein-containing Complex Transcription Initiation At RNA Polymerase I Promoter Nucleus Chromatin Remodeling Nuclear Receptor-mediated Signaling Pathway Transcription Coregulator Binding Estrogen Response Element Binding Transcription Coactivator Binding Regulation Of Signal Transduction By P53 Class Mediator Transcription By RNA Polymerase I Enzyme Binding Euchromatin Core Promoter Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Hormone-mediated Signaling Pathway Nucleic Acid Metabolic Process Cellular Component Assembly Epigenetic Regulation Of Gene Expression Nuclear Steroid Receptor Activity Regulation Of MiRNA Transcription DNA-templated Transcription Initiation Positive Regulation Of RNA Metabolic Process Chromosome Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Initiation Structural Constituent Of Chromatin Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To UV Regulation Of MiRNA Metabolic Process	Transcription By RNA Polymerase I RNA Polymerase Transcription Factor SL1 Complex DNA-templated Transcription Nucleolus RRNA Transcription Nucleoplasm Cyclin E1-CDK2 Complex RNA Polymerase I Transcription Regulator Complex Nucleolar Large RRNA Transcription By RNA Polymerase I Nucleobase-containing Compound Biosynthetic Process Macromolecule Biosynthetic Process DNA/RNA Hybrid Binding 5'-3' RNA Polymerase Activity RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I Preinitiation Complex Assembly RNA Polymerase I Complex Nucleic Acid Metabolic Process RNA Metabolic Process Macromolecule Metabolic Process Fibrillar Center Nucleobase-containing Compound Metabolic Process DNA-directed RNA Polymerase Activity DNA-directed RNA Polymerase Complex Cyclin-dependent Protein Kinase Holoenzyme Complex RRNA Metabolic Process Transcription Preinitiation Complex Assembly RNA Polymerase I Core Factor Complex Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Y Chromosome Positive Regulation Of Heterochromatin Formation Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Negative Regulation Of Protein Localization To Nucleolus Nucleologenesis Nucleotidyltransferase Activity Telomere Maintenance Positive Regulation Of Chromatin Organization Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Ribonucleoside Binding X Chromosome Telomere Organization Stereocilium Membrane RNA Polymerase I General Transcription Initiation Factor Activity Viral Translational Termination-reinitiation Mitotic Cell Cycle Phase Transition Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Histone Kinase Activity
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