TAF1B and NAPB

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TAF1B	NAPB
Gene Name		TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	N-ethylmaleimide-sensitive factor attachment protein, beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Extracellular Vesicular Exosome RNA Polymerase I Core Factor Complex	Vacuolar Membrane SNARE Complex Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase I CORE Element Sequence-specific DNA Binding RNA Polymerase I CORE Element Sequence-specific DNA Binding Transcription Factor Recruiting Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding TBP-class Protein Binding Metal Ion Binding	Soluble NSF Attachment Protein Activity Syntaxin Binding
	Biological Process	Chromatin Silencing At RDNA RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript Transcription, DNA-templated Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Intracellular Protein Transport SNARE Complex Disassembly Membrane Fusion
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression SIRT1 negatively regulates rRNA Expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		24 interactors: APP EP300 ESR1 HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MYC NAPB NEDD4 NEDD4L PGR RRN3 RXRA SRPK1 TAF1A TAF1C TAF1D TBP THAP7 TP53 TRB TRIM24 UBTF	10 interactors: ARL6IP1 SNAP23 STX16 STX1A STX3 STX4 STX5 STX6 TAF1B TFEC
Entrez ID		9014	63908
HPRD ID		05363	17627
Ensembl ID		ENSG00000115750	ENSG00000125814
Uniprot IDs		Q53T94	Q4G0M0 Q9H115
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression DNA-templated Transcription, Initiation Chromatin Silencing At RDNA Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Transcription Initiation From RNA Polymerase I Promoter Negative Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase I Promoter Negative Regulation Of Gene Expression, Epigenetic Gene Expression Chromatin Silencing Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase I Transcription Negative Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Silencing Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Termination Positive Regulation Of Transcription, DNA-templated Chromatin Organization Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Macromolecule Biosynthetic Process Chromosome Organization Viral Process DNA Packaging Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Biosynthetic Process DNA Conformation Change	Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Organization Membrane Docking Synaptic Vesicle Exocytosis Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Golgi Vesicle Transport Protein Localization Neurotransmitter Secretion Synaptic Vesicle Transport Establishment Of Localization In Cell Cellular Protein Localization Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Cellular Localization Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Localization Retrograde Transport, Endosome To Golgi Golgi Ribbon Formation Positive Regulation Of Protein Localization To Cell Surface Golgi Organization Establishment Of Organelle Localization Exocytosis Positive Regulation Of Synaptic Transmission Organelle Localization Regulation Of Protein Localization To Cell Surface Secretion By Cell Positive Regulation Of Protein Localization To Plasma Membrane Organelle Organization Synaptic Transmission Endosomal Transport Secretion Transport Long-term Synaptic Potentiation Regulation Of Protein Localization Regulation Of Protein Localization To Plasma Membrane Regulation Of Synaptic Transmission Positive Regulation Of Exocytosis Cell-cell Signaling Post-Golgi Vesicle-mediated Transport Endomembrane System Organization RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Tagcloud ?		analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1c tata tbp tumourigenesis ubf	abeta42 accordingly accumulations aggregates approved autophagy bioavailable enduring experimentally fda fiber fibers ibm inclusion lysosomal muscle myositis oligomers orally pathologically phenylbutyrate recapitulate reverses secretase sporadic urea vacuolated vacuolization virtually
Tagcloud (Difference) ?		analysed blocking c8 coding crc frameshift gc harboured heterogeneity instability intratumoural ith microsatellite mononucleotide msi mss mutational regional ribosomal rrna somatic strand summary taf1a taf1c tata tbp tumourigenesis ubf	abeta42 accordingly accumulations aggregates approved autophagy bioavailable enduring experimentally fda fiber fibers ibm inclusion lysosomal muscle myositis oligomers orally pathologically phenylbutyrate recapitulate reverses secretase sporadic urea vacuolated vacuolization virtually
Tagcloud (Intersection) ?