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C7orf25 and MTOR
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
C7orf25
MTOR
Gene Name
chromosome 7 open reading frame 25
mechanistic target of rapamycin (serine/threonine kinase)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Lysosome
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Cytosol
Phosphatidylinositol 3-kinase Complex
Endomembrane System
Membrane
PML Body
Dendrite
TORC1 Complex
TORC2 Complex
Neuronal Cell Body
Molecular Function
RNA Polymerase III Type 1 Promoter DNA Binding
RNA Polymerase III Type 2 Promoter DNA Binding
RNA Polymerase III Type 3 Promoter DNA Binding
TFIIIC-class Transcription Factor Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Drug Binding
Kinase Activity
Protein Domain Specific Binding
Ribosome Binding
Protein Dimerization Activity
Phosphoprotein Binding
Biological Process
Double-strand Break Repair Via Homologous Recombination
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Endothelial Cell Proliferation
Regulation Of Glycogen Biosynthetic Process
Protein Phosphorylation
Response To Stress
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Germ Cell Development
Response To Nutrient
Insulin Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Autophagy
Positive Regulation Of Lamellipodium Assembly
Positive Regulation Of Gene Expression
Positive Regulation Of Myotube Differentiation
Cell Growth
Negative Regulation Of Macroautophagy
Phosphorylation
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Protein Catabolic Process
Positive Regulation Of Actin Filament Polymerization
T Cell Costimulation
Ruffle Organization
Regulation Of Myelination
Cellular Response To Nutrient Levels
TOR Signaling
Regulation Of Fatty Acid Beta-oxidation
Regulation Of Response To Food
Regulation Of Rac GTPase Activity
Regulation Of Actin Cytoskeleton Organization
Cellular Response To Heat
Fc-epsilon Receptor Signaling Pathway
Growth
Response To Amino Acid
Regulation Of Carbohydrate Utilization
Innate Immune Response
Positive Regulation Of Translation
Negative Regulation Of Cell Size
Regulation Of Protein Kinase Activity
Positive Regulation Of Transcription From RNA Polymerase III Promoter
Protein Autophosphorylation
Positive Regulation Of Lipid Biosynthetic Process
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Stress Fiber Assembly
Negative Regulation Of NFAT Protein Import Into Nucleus
Positive Regulation Of Protein Kinase B Signaling
Cellular Response To Hypoxia
Regulation Of Cellular Response To Heat
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by FGFR in disease
mTOR signalling
Signaling by EGFRvIII in Cancer
Signaling by SCF-KIT
Downstream signaling events of B Cell Receptor (BCR)
DAP12 signaling
PI3K/AKT activation
PI-3K cascade
PKB-mediated events
PI3K Cascade
Signaling by PDGF
DAP12 interactions
GAB1 signalosome
CD28 co-stimulation
CD28 dependent PI3K/Akt signaling
Signaling by ERBB4
Role of LAT2/NTAL/LAB on calcium mobilization
Constitutive PI3K/AKT Signaling in Cancer
PI3K events in ERBB4 signaling
S6K1-mediated signalling
mTORC1-mediated signalling
Signaling by ERBB2
Signaling by EGFR
Signaling by VEGF
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Costimulation by the CD28 family
IRS-mediated signalling
PIP3 activates AKT signaling
mTOR signalling
S6K1-mediated signalling
mTORC1-mediated signalling
IGF1R signaling cascade
VEGFA-VEGFR2 Pathway
HSF1-dependent transactivation
IRS-related events triggered by IGF1R
PI3K events in ERBB2 signaling
Release of eIF4E
VEGFR2 mediated vascular permeability
Downstream signaling of activated FGFR
Signaling by Insulin receptor
Innate Immune System
Signalling by NGF
Insulin receptor signalling cascade
IRS-related events
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Cellular response to heat stress
Release of eIF4E
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
PKB-mediated events
PI3K Cascade
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
BRD4
CEP70
CRYM
DACT1
EZH2
FRA10AC1
FYN
FZR1
HAP1
HEXDC
MTOR
NGEF
PTN
RASSF1
RPL36AL
SF3B2
TARS
UBE2D1
42 interactors:
AKT1
AKT1S1
AMBRA1
BCL2L1
C7orf25
CDC37
CFP
CLIP1
EIF3F
EIF4EBP1
EIF4EBP2
FKBP1A
FKBP8
GPHN
GSK3B
IRS1
MAF1
MLST8
PA2G4
PDPK1
PLD2
PPP2R2A
PREX1
PRKAA1
PRKCA
PRR5L
RHEB
RHEBL1
RICTOR
RPS6KA1
RPS6KB1
RPS6KB2
RPTOR
RRAGB
RRAGD
SEPT2
STAT3
TELO2
TERT
TRAF6
UBQLN1
YWHAQ
Entrez ID
79020
2475
HPRD ID
09861
03134
Ensembl ID
ENSG00000136197
ENSG00000198793
Uniprot IDs
Q9BPX7
B4DZD5
P42345
PDB IDs
1AUE
1FAP
1NSG
2FAP
2GAQ
2NPU
2RSE
3FAP
4DRH
4DRI
4DRJ
4FAP
4JSN
4JSP
4JSV
4JSX
4JT5
4JT6
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Cycle Process
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle
Cell Cycle Process
Regulation Of Protein Metabolic Process
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Cell Cycle
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Cellular Response To Stress
Regulation Of Intracellular Signal Transduction
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination
Regulation Of Cell Cycle G1/S Phase Transition
Regulation Of Protein Catabolic Process
Mitotic Cell Cycle
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Metabolic Process
Regulation Of Cellular Component Organization
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Cell Differentiation
Posttranscriptional Regulation Of Gene Expression
Regulation Of Cell Morphogenesis
Regulation Of Protein Localization To Nucleus
Regulation Of Cell Projection Organization
Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cell Differentiation
Regulation Of DNA-templated Transcription, Elongation
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Division
Positive Regulation Of Neurotrophin Production
Regulation Of Carbohydrate Utilization
Positive Regulation Of Nonmotile Primary Cilium Assembly
Positive Regulation Of Cell Cycle Phase Transition
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Positive Regulation Of Cellular Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of TOR Signaling
Neurotrophin TRK Receptor Signaling Pathway
Cellular Response To Organic Substance
Neurotrophin Signaling Pathway
Regulation Of Signaling
Cellular Response To Organonitrogen Compound
Positive Regulation Of Signal Transduction
TOR Signaling
Insulin Receptor Signaling Pathway
Response To Organic Substance
Regulation Of Metabolic Process
Response To Organonitrogen Compound
Cellular Response To Growth Factor Stimulus
Regulation Of Protein Metabolic Process
Response To Growth Factor
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of TOR Signaling
Phosphatidylinositol-mediated Signaling
Cellular Response To Insulin Stimulus
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Epidermal Growth Factor Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Intracellular Signal Transduction
Fc Receptor Signaling Pathway
Cellular Response To Stimulus
Cellular Response To Fibroblast Growth Factor Stimulus
Innate Immune Response
Response To Fibroblast Growth Factor
Cell Communication
Response To Insulin
Regulation Of Immune Response
Fc-epsilon Receptor Signaling Pathway
Regulation Of Cell Death
Response To Peptide Hormone
Immune Response-regulating Signaling Pathway
Signal Transduction
Negative Regulation Of Cell Death
Response To Peptide
Regulation Of Cellular Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Apoptotic Process
Signaling
Regulation Of Immune System Process
Tagcloud
?
aib
aminoisobutyric
ars
arsenite
carrier
hormonal
hs
hyperthermic
instigate
involve
k2
km
l6
map
mapkap
maximally
metabolisable
p42
p44
phosphoinositide
pi3k
rapamycin
sapk2
sb
stresses
transport
transporter
vmax
whilst
wortmannin
Tagcloud (Difference)
?
aib
aminoisobutyric
ars
arsenite
carrier
hormonal
hs
hyperthermic
instigate
involve
k2
km
l6
map
mapkap
maximally
metabolisable
p42
p44
phosphoinositide
pi3k
rapamycin
sapk2
sb
stresses
transport
transporter
vmax
whilst
wortmannin
Tagcloud (Intersection)
?