C7orf25 and CRYM

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		C7orf25	CRYM
Description		chromosome 7 open reading frame 25	crystallin mu
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Mitochondrion Peroxisomal Matrix Cytosol Extracellular Exosome
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding Oxidoreductase Activity Hormone Binding Protein Homodimerization Activity Delta1-piperideine-2-carboxylate Reductase Activity Thiomorpholine-carboxylate Dehydrogenase Activity NADP Binding Thyroid Hormone Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Sensory Perception Of Sound Thyroid Hormone Metabolic Process Thyroid Hormone Transport
Pathways			Lysine catabolism
Drugs			NRP409
Diseases
GWAS		Asthma ( 29273806) Ceramide levels (C24:0) ( 32489964)	Pelvic organ prolapse ( 26545240)
Interacting Genes		20 interacting genes: BRD4 CEP70 CRYM DACT1 EZH2 FRA10AC1 FYN FZR1 GTPBP1 HAP1 HEXD MTOR MX1 NGEF PTN RASSF1 RPL36AL SF3B2 TARS1 UBE2D1	5 interacting genes: ADRB2 C7orf25 CDC37 TERF1 TG
Entrez ID		79020	1428
HPRD ID		09861	08831
Ensembl ID		ENSG00000136197	ENSG00000103316
Uniprot IDs		Q9BPX7	Q14894
PDB IDs			2I99
Enriched GO Terms of Interacting Partners?		Regulation Of Plasma Membrane Bounded Cell Projection Organization Negative Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Projection Organization Regulation Of Protein Metabolic Process Positive Regulation Of Dendrite Development Regulation Of Cell Projection Organization Regulation Of Protein Ubiquitination Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Metabolic Process Regulation Of Gliogenesis Positive Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Protein Ubiquitination Cytoplasmic Translation Ephrin Receptor Binding Positive Regulation Of Post-translational Protein Modification Delta1-piperideine-2-carboxylate Reductase Activity Nucleus Thiomorpholine-carboxylate Dehydrogenase Activity Regulation Of Cellular Component Organization Positive Regulation Of Neuron Projection Development Positive Regulation Of Protein Modification Process Hepatocyte Homeostasis Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Protein Modification Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Neurogenesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Translation Transmembrane Transporter Binding Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Glial Cell Differentiation Regulation Of Protein Catabolic Process Pyrimidine-containing Compound Biosynthetic Process Regulation Of Oligodendrocyte Differentiation Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Cellular Response To Glycine Response To Singlet Oxygen Positive Regulation Of Neurotrophin Production Histone H4K8ac Reader Activity Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Myelination T Cell Costimulation Regulation Of Cell Cycle Process Regulation Of Neuron Projection Development Cellular Response To Stress Regulation Of Nervous System Development Positive Regulation Of Cell Development Dendrite Morphogenesis Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway	Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of Macroautophagy Beta2-adrenergic Receptor Activity Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication HSP90-CDC37 Chaperone Complex Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Norepinephrine Binding Response To Psychosocial Stress Positive Regulation Of Autophagy Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Regulation Of Macroautophagy Positive Regulation Of Autophagosome Maturation Heat Generation Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Shelterin Complex Ankyrin Repeat Binding Iodide Transport Adrenergic Receptor Activity Nuclear Telomere Cap Complex Telomere Localization Meiotic Telomere Clustering Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Diet Induced Thermogenesis G-rich Strand Telomeric DNA Binding Adenylate Cyclase Binding Negative Regulation Of Smooth Muscle Contraction T-circle Formation Telomeric Loop Disassembly Telomere Capping Positive Regulation Of Type 2 Mitophagy Negative Regulation Of Multicellular Organism Growth Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Thyroid Hormone Generation Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Regulation Of Autophagosome Maturation Positive Regulation Of CAMP/PKA Signal Transduction DNA Binding, Bending
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