SAPCD2 and GPRASP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SAPCD2	GPRASP2
Description		suppressor APC domain containing 2	G protein-coupled receptor associated sorting protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Bicellular Tight Junction Cell Cortex Membrane Apical Plasma Membrane Apical Junction Complex Apical Cortex Anchoring Junction	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Positive Regulation Of Cell Population Proliferation Cell Division Regulation Of Establishment Of Planar Polarity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex	Hematopoietic Stem Cell Homeostasis
Pathways
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494)
Interacting Genes		13 interacting genes: AIRIM ATF4 BFSP2 CYSRT1 EXOC7 GMNN GPRASP2 KRT3 KRTAP1-3 MDFI RALBP1 USHBP1 VCL	52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 DSCR9 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688
Entrez ID		89958	114928
HPRD ID		12943	06612
Ensembl ID		ENSG00000186193	ENSG00000158301
Uniprot IDs		Q86UD0	B3KW05 Q96D09
PDB IDs
Enriched GO Terms of Interacting Partners?			G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Trans-synaptic Signaling G Protein-coupled Acetylcholine Receptor Activity Synaptic Signaling Neuromuscular Synaptic Transmission Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Export From Nucleus Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Microtubule Cytoskeleton Organization Cholinergic Synapse Dendrite
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