SELENBP1 and MED31

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SELENBP1	MED31
Description		selenium binding protein 1	mediator complex subunit 31
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Membrane Extracellular Exosome	Ubiquitin Ligase Complex Nucleus Nucleoplasm Mediator Complex Core Mediator Complex
	Molecular Function	Protein Binding Selenium Binding Oxidoreductase Activity Methanethiol Oxidase Activity	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Transport	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation RNA Polymerase II Preinitiation Complex Assembly Limb Development Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways			PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494) Lymphocyte count ( 32888494) Red cell distribution width ( 32888494)	LDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883)
Interacting Genes		13 interacting genes: BARD1 EED GORASP2 GPX1 LRIF1 MED31 MLH1 MSRA POLDIP2 RPA1 TRA2A TRIP13 USP33	58 interacting genes: AGR2 ANXA7 ASCC2 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED8 MED9 MOB4 NAF1 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 TLE5 UBE2B WDCP ZBTB45 ZSCAN1
Entrez ID		8991	51003
HPRD ID		05007	14382
Ensembl ID		ENSG00000143416	ENSG00000108590
Uniprot IDs		Q13228 V9HWG1	Q9Y3C7
PDB IDs			7EMF 7ENA 7ENC 7ENJ 7LBM 7NVR 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Homologous Recombination Male Germ Cell Nucleus Cellular Response To Stress Response To Stress DNA Repair DNA Recombination Meiotic Nuclear Division Nuclear Division Meiotic Cell Cycle Reciprocal Meiotic Recombination DNA Metabolic Process Mismatch Repair Regulation Of Meiotic Nuclear Division DNA Damage Response Condensed Chromosome Negative Regulation Of MRNA 3'-end Processing Chromatin Organization Zymogen Binding Cell Development Double-strand Break Repair Male Meiotic Nuclear Division Condensed Nuclear Chromosome Oogenesis Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment L-methionine:thioredoxin-disulfide S-oxidoreductase Activity Peptide-methionine (S)-S-oxide Reductase Activity L-methionine-(S)-S-oxide Reductase Activity Receptor Tyrosine Kinase-like Orphan Receptor Binding Chemoattraction Of Serotonergic Neuron Axon Negative Regulation Of Cell Proliferation In Midbrain Optic Cup Formation Involved In Camera-type Eye Development Chromosome Organization Involved In Meiotic Cell Cycle Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Cellular Developmental Process Epigenetic Regulation Of Gene Expression Meiotic Spindle Midzone Assembly Female Gamete Generation Meiosis I Cell Cycle Process Meiotic Metaphase Chromosome Alignment Chiasma Regulation Of Meiotic Cell Cycle Postsynapse Assembly Hypophysis Morphogenesis Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Timing Of Anagen Chemoattractant Activity Involved In Axon Guidance Cervix Development	Nucleus Core Mediator Complex Mediator Complex RNA Polymerase II Preinitiation Complex Assembly Identical Protein Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Transcription Elongation By RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Binding Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of DNA Biosynthetic Process Regulation Of DNA-templated Transcription Elongation Nucleoplasm
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