SELENBP1 and MED31

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SELENBP1	MED31
Gene Name		selenium binding protein 1	mediator complex subunit 31
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleolus Cytosol Membrane Extracellular Vesicular Exosome	Nucleoplasm Mediator Complex
	Molecular Function	Protein Binding Selenium Binding	RNA Polymerase II Transcription Cofactor Activity Protein Binding Protein Complex Binding
	Biological Process	Protein Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Protein Complex Assembly Gene Expression Negative Regulation Of Fibroblast Proliferation Limb Development
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494)
Protein-Protein Interactions		12 interactors: BARD1 EED GORASP2 GPX1 LRIF1 MED31 MLH1 POLDIP2 RPA1 TRA2A TRIP13 USP33	58 interactors: AES AGR2 ANXA7 ASCC2 C2orf44 CACNB4 CCT7 CDKN1A CPE DAZAP2 DLEU1 DNM1 EEF1G EGR2 EPN1 ERH FAM118B GADD45G GSTM4 HGH1 HMOX2 HNRNPUL1 HSPB1 HSPB3 HTT LAMA4 LYPLA2 MAFG MED18 MED19 MED7 MED8 MED9 MOB4 NFATC2 NR4A1 ORAI2 PABPC4 PAFAH1B3 PFDN1 PMF1 PQBP1 PRMT1 PSMD11 RAB25 RBM23 RFC5 RPA2 SAT1 SELENBP1 SERPINB9 SMN1 TGIF1 TINAGL1 TK1 UBE2B ZBTB45 ZSCAN1
Entrez ID		8991	51003
HPRD ID		05007	14382
Ensembl ID		ENSG00000143416	ENSG00000108590
Uniprot IDs		A6PVW9 Q13228	Q9Y3C7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cellular Response To Stress Nucleobase-containing Compound Metabolic Process Double-strand Break Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Meiotic Nuclear Division Cell Cycle Process Cellular Nitrogen Compound Metabolic Process Meiotic Cell Cycle DNA Repair DNA Recombination Multicellular Organismal Homeostasis Nitrogen Compound Metabolic Process Reciprocal Meiotic Recombination Organelle Organization Synapsis Mismatch Repair Homologous Chromosome Segregation Male Meiosis Meiotic Spindle Midzone Assembly Positive Regulation Of Fibril Organization Meiotic Metaphase I Plate Congression Cellular Response To DNA Damage Stimulus Oogenesis Meiotic Chromosome Segregation Regulation Of Protein Catabolic Process Negative Regulation Of Mitotic Recombination Negative Regulation Of MRNA 3'-end Processing Response To Symbiotic Bacterium Chromosome Organization Meiosis I Aromatic Compound Catabolic Process Female Gamete Generation DNA Metabolic Process Regulation Of Fibril Organization Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Response To Lipid Hydroperoxide DNA Recombinase Assembly RNA Metabolic Process Myoblast Proliferation Negative Regulation Of Protein Export From Nucleus Protein Oxidation Response To Selenium Ion Tissue Homeostasis Response To Stress Gene Expression Protein K6-linked Ubiquitination Intrinsic Apoptotic Signaling Pathway	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Developmental Process Biosynthetic Process Regulation Of Gene Expression Anatomical Structure Development Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Differentiation Multicellular Organismal Development Response To Stimulus Neurotransmitter Uptake Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nucleotide-excision Repair, DNA Gap Filling Negative Regulation Of Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Programmed Cell Death Telomere Maintenance Via Semi-conservative Replication System Development Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Cell Death Telomere Maintenance Via Recombination Nuclear DNA Replication Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Embryo Development Ending In Birth Or Egg Hatching DNA-templated Transcription, Initiation Response To External Stimulus Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		aci arthritis ccl2 chemicals cia10 cia25 cia3d cia5a cigarette clec4m congenic congenics core correlating da erosive f344 mediators nonerosive nongenetic nongenetically rheumatoid scd1 slc7a10 spond1 synovial tnn upstream xenobiotic
Tagcloud (Difference) ?		aci arthritis ccl2 chemicals cia10 cia25 cia3d cia5a cigarette clec4m congenic congenics core correlating da erosive f344 mediators nonerosive nongenetic nongenetically rheumatoid scd1 slc7a10 spond1 synovial tnn upstream xenobiotic
Tagcloud (Intersection) ?