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TSC22D1 and GNB5
Number of citations of the paper that reports this interaction (PMID
21900206
)
27
Data Source:
BioGRID
(two hybrid)
TSC22D1
GNB5
Gene Name
TSC22 domain family, member 1
guanine nucleotide binding protein (G protein), beta 5
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Nucleus
Plasma Membrane
Molecular Function
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
GTPase Activity
Signal Transducer Activity
Protein Binding
G-protein Gamma-subunit Binding
Chaperone Binding
Biological Process
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cell Proliferation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Signal Transduction
Phototransduction, Visible Light
Metabolic Process
Rhodopsin Mediated Signaling Pathway
Regulation Of Rhodopsin Mediated Signaling Pathway
Negative Regulation Of Voltage-gated Calcium Channel Activity
Pathways
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
G alpha (s) signalling events
Glucagon-type ligand receptors
Signal amplification
Signaling by Wnt
G beta:gamma signalling through PLC beta
Metabolic disorders of biological oxidation enzymes
G beta:gamma signalling through PI3Kgamma
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
G alpha (z) signalling events
G alpha (12/13) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Class B/2 (Secretin family receptors)
ADP signalling through P2Y purinoceptor 12
Prostacyclin signalling through prostacyclin receptor
G-protein beta:gamma signalling
Vasopressin regulates renal water homeostasis via Aquaporins
Opioid Signalling
Regulation of insulin secretion
Activation of Kainate Receptors upon glutamate binding
GPCR ligand binding
Aquaporin-mediated transport
beta-catenin independent WNT signaling
Adrenaline,noradrenaline inhibits insulin secretion
Thrombin signalling through proteinase activated receptors (PARs)
G alpha (q) signalling events
Presynaptic function of Kainate receptors
GPCR downstream signaling
Platelet homeostasis
Ca2+ pathway
G-protein activation
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Protein-Protein Interactions
49 interactors:
A2M
APLP1
ASAH1
C14orf1
C9orf9
CACNA1A
CARHSP1
CCDC90B
CHD3
CORO2B
CRMP1
DDAH2
DNMT3B
EED
FAF1
FAM20C
FBN3
GNB2
GNB5
HMGXB4
KMT2B
KMT2C
LRIF1
MAP3K12
MCM3AP
NCOA5
OTUB1
PDHB
PRKCI
PTN
QARS
RGS1
RPL5
SETDB1
SP110
SPRED1
TAF5L
TGFBR1
TLE1
TP53
TSC22D4
UBE2D1
UNC119
VIM
WDR73
WDYHV1
WIZ
WNK1
ZC3HC1
26 interactors:
ANXA7
APP
BNIP3L
CDKN1A
CSNK2B
E2F2
EIF3J
GNG13
GNG2
GNG3
GNG4
GNG5
GNG7
GNGT1
MCM2
MVD
NR6A1
OLFM2
PSD
PSMD4
RGS11
RGS6
RGS7
RGS9
RPA1
TSC22D1
Entrez ID
8848
10681
HPRD ID
07414
09191
Ensembl ID
ENSG00000069966
Uniprot IDs
A8K3Y6
Q15714
B3KWS4
O14775
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Chromatin Organization
Chromatin Modification
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Cellular Process
Regulation Of Cellular Protein Metabolic Process
Chromosome Organization
Regulation Of Chromosome Organization
Regulation Of Histone Modification
Regulation Of Protein Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Histone Methylation
Histone Modification
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Peptidyl-threonine Phosphorylation
RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Signal Transduction
Heterocycle Metabolic Process
Regulation Of Histone Methylation
Cellular Aromatic Compound Metabolic Process
Regulation Of Cellular Component Organization
Signal Transduction
Transcription, DNA-templated
Cellular Response To Stimulus
Negative Regulation Of Signaling
Regulation Of Phosphorus Metabolic Process
Response To Stimulus
Protein Methylation
Positive Regulation Of Histone Modification
Regulation Of Transcription, DNA-templated
Organelle Organization
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Signaling
Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Gene Expression
Cell Communication
Histone Lysine Methylation
Negative Regulation Of Chromosome Organization
Negative Regulation Of Cellular Protein Metabolic Process
Cellular Response To Glucagon Stimulus
Response To Glucagon
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Energy Reserve Metabolic Process
G-protein Coupled Receptor Signaling Pathway
Response To Hormone
Cellular Response To Stimulus
Signal Transduction
Cellular Response To Hormone Stimulus
Signaling
Cell Communication
Response To Stimulus
Regulation Of Cellular Process
Termination Of G-protein Coupled Receptor Signaling Pathway
Termination Of Signal Transduction
Energy Derivation By Oxidation Of Organic Compounds
Cell Surface Receptor Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Response To Organic Substance
Generation Of Precursor Metabolites And Energy
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Response To Peptide
Regulation Of Signal Transduction
Cellular Response To Organic Substance
Regulation Of Catalytic Activity
Positive Regulation Of Catalytic Activity
Response To Organonitrogen Compound
G1/S Transition Of Mitotic Cell Cycle
Synaptic Transmission
Regulation Of Signaling
Mitotic Cell Cycle
Cellular Response To Light Stimulus
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Signal Transduction By P53 Class Mediator
Regulation Of Metabolic Process
Cell-cell Signaling
Regulation Of Rhodopsin Mediated Signaling Pathway
Positive Regulation Of Metabolic Process
Response To Light Stimulus
DNA Strand Elongation Involved In DNA Replication
Cellular Process
Cellular Response To Radiation
Apoptotic Process
DNA Strand Elongation
Small Molecule Metabolic Process
Rhodopsin Mediated Signaling Pathway
Tagcloud
?
beadchip
capn13
cards
cic
collect
conjunctival
cxcl6
cytology
drb5
dry
entire
eye
ht
illumina
impression
investigates
lysozyme
mini
optimally
optimization
psca
qiagen
qrt
qualifying
rneasy
severities
steps
taqman
transcriptome
Tagcloud (Difference)
?
beadchip
capn13
cards
cic
collect
conjunctival
cxcl6
cytology
drb5
dry
entire
eye
ht
illumina
impression
investigates
lysozyme
mini
optimally
optimization
psca
qiagen
qrt
qualifying
rneasy
severities
steps
taqman
transcriptome
Tagcloud (Intersection)
?