SEC13

Gene Name		SEC13 homolog (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Kinetochore Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Nuclear Pore Outer Ring Extracellular Vesicular Exosome
	Molecular Function	Protein Binding
	Biological Process	Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating MRNA Transport Membrane Organization
Pathways		Mitotic Prometaphase Diseases of glycosylation Separation of Sister Chromatids Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Mitotic Anaphase Antigen Presentation: Folding, assembly and peptide loading of class I MHC M Phase Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Cell Cycle, Mitotic Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Resolution of Sister Chromatid Cohesion Defective ALG12 causes ALG12-CDG (CDG-1g) Mitotic Metaphase and Anaphase Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: CLDN12 EGFR NUP98 RAB11A SEC16B SEC31A TRAF5 WDR44
Entrez ID		6396
HPRD ID		02538
Ensembl ID		ENSG00000157020
Uniprot IDs		A8MWR8 B4DXJ1 P55735
PDB IDs		3BG0 3BG1
Enriched GO Terms of Interacting Partners?		Membrane Organization COPII Vesicle Coating COPII-coated Vesicle Budding Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Cytoplasmic Transport Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Cellular Component Assembly Protein Localization Establishment Of Organelle Localization Protein Complex Assembly Organelle Localization Cellular Localization Endomembrane System Organization Membrane Budding Alkanesulfonate Metabolic Process Regulation Of Multivesicular Body Size Multivesicular Body Assembly Cellular Protein Localization Protein Localization To Organelle ER To Golgi Vesicle-mediated Transport Protein Transport Response To Calcium Ion Intracellular Transport Protein Import Into Nucleus, Docking Multivesicular Body Organization Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Endosome Size Positive Regulation Of Intracellular Protein Transport Mitotic Cell Cycle Activation Of Phospholipase A2 Activity Exosomal Secretion Regulation Of Protein Localization Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Protein Exit From Endoplasmic Reticulum Establishment Of Localization In Cell Vesicle Organization Response To Cobalamin Response To UV-A Regulation Of Protein Exit From Endoplasmic Reticulum Response To Hydroxyisoflavone Nuclear Pore Complex Assembly Establishment Of Protein Localization To Membrane
Tagcloud ?		antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses