SEC13 and SEC31A

Number of citations of the paper that reports this interaction (PMID 10788476)
24

Data Source:
HPRD (in vivo)

		SEC13	SEC31A
Gene Name		SEC13 homolog (S. cerevisiae)	SEC31 homolog A (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Kinetochore Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Nuclear Pore Outer Ring Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Vesicle Coat COPII Vesicle Coat ER To Golgi Transport Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	Protein Binding Calcium-dependent Protein Binding
	Biological Process	Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating MRNA Transport Membrane Organization	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I ER To Golgi Vesicle-mediated Transport Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Protein Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Post-translational Protein Modification Cellular Protein Metabolic Process COPII Vesicle Coating Response To Calcium Ion Membrane Organization
Pathways		Mitotic Prometaphase Diseases of glycosylation Separation of Sister Chromatids Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Mitotic Anaphase Antigen Presentation: Folding, assembly and peptide loading of class I MHC M Phase Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Cell Cycle, Mitotic Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Resolution of Sister Chromatid Cohesion Defective ALG12 causes ALG12-CDG (CDG-1g) Mitotic Metaphase and Anaphase Diseases associated with N-glycosylation of proteins Adaptive Immune System	Diseases of glycosylation Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Antigen Presentation: Folding, assembly and peptide loading of class I MHC XBP1(S) activates chaperone genes Defective MOGS causes MOGS-CDG (CDG-2b) IRE1alpha activates chaperones Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Unfolded Protein Response (UPR) Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CLDN12 EGFR NUP98 RAB11A SEC16B SEC31A TRAF5 WDR44	5 interactors: APC PFDN1 REL SEC13 TNNT1
Entrez ID		6396	22872
HPRD ID		02538	15314
Ensembl ID		ENSG00000157020	ENSG00000138674
Uniprot IDs		A8MWR8 B4DXJ1 P55735	B7ZL00 D6REX3 H7BXG7 O94979
PDB IDs		3BG0 3BG1
Enriched GO Terms of Interacting Partners?		Membrane Organization COPII Vesicle Coating COPII-coated Vesicle Budding Establishment Of Protein Localization Establishment Of Vesicle Localization Vesicle Localization Cytoplasmic Transport Vesicle Targeting, To, From Or Within Golgi Vesicle Targeting Localization Within Membrane Cellular Component Assembly Protein Localization Establishment Of Organelle Localization Protein Complex Assembly Organelle Localization Cellular Localization Endomembrane System Organization Membrane Budding Alkanesulfonate Metabolic Process Regulation Of Multivesicular Body Size Multivesicular Body Assembly Cellular Protein Localization Protein Localization To Organelle ER To Golgi Vesicle-mediated Transport Protein Transport Response To Calcium Ion Intracellular Transport Protein Import Into Nucleus, Docking Multivesicular Body Organization Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Endosome Size Positive Regulation Of Intracellular Protein Transport Mitotic Cell Cycle Activation Of Phospholipase A2 Activity Exosomal Secretion Regulation Of Protein Localization Positive Regulation Of Phospholipase A2 Activity Positive Regulation Of Protein Exit From Endoplasmic Reticulum Establishment Of Localization In Cell Vesicle Organization Response To Cobalamin Response To UV-A Regulation Of Protein Exit From Endoplasmic Reticulum Response To Hydroxyisoflavone Nuclear Pore Complex Assembly Establishment Of Protein Localization To Membrane
Tagcloud ?		antagonized borne brefeldin collectively copii delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding sec31a spread tension termed tuba uses	a11 alg anxa11 apparatus architectural associates cage cargo cargoes coat coordinating copii ef eres exit golgi juxtanuclear maintains penta periphery physically scattering secretory specialized stabilize synchronous trafficking vesicle vesicular
Tagcloud (Difference) ?		antagonized borne brefeldin collectively delivering depletion enterocytes imposed inlc junctions listeria monocytogenes motile motility otherwise perturbed precipitation protrusion protrusions relieves sar1 scaffolding spread tension termed tuba uses	a11 alg anxa11 apparatus architectural associates cage cargo cargoes coat coordinating ef eres exit golgi juxtanuclear maintains penta periphery physically scattering secretory specialized stabilize synchronous trafficking vesicle vesicular
Tagcloud (Intersection) ?		copii sec31a