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SEC13 and NUP98
Number of citations of the paper that reports this interaction (PubMedID
35271311
)
106
Data Source:
BioGRID
(affinity chromatography technology, biochemical)
HPRD
(two hybrid, in vitro)
SEC13
NUP98
Description
SEC13 homolog, nuclear pore and COPII component
nucleoporin 98 and 96 precursor
Image
GO Annotations
Cellular Component
Kinetochore
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Lysosome
Lysosomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Membrane
COPII Vesicle Coat
Nuclear Pore Outer Ring
Cytoplasmic Vesicle
GATOR2 Complex
Extracellular Exosome
Kinetochore
Nucleus
Nuclear Envelope
Nuclear Pore
Nucleoplasm
Cytosol
Membrane
Nuclear Body
Nuclear Pore Outer Ring
Nuclear Membrane
Nuclear Periphery
Nuclear Inclusion Body
Nuclear Pore Cytoplasmic Filaments
Nuclear Pore Nuclear Basket
Ribonucleoprotein Complex
Molecular Function
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Transcription Coactivator Activity
RNA Binding
MRNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Structural Constituent Of Nuclear Pore
Peptide Binding
Molecular Condensate Scaffold Activity
Promoter-specific Chromatin Binding
Biological Process
Protein Import Into Nucleus
Intracellular Protein Transport
Nucleocytoplasmic Transport
Protein Transport
Vesicle-mediated Transport
Cellular Response To Nutrient Levels
Positive Regulation Of TOR Signaling
Protein Exit From Endoplasmic Reticulum
MRNA Transport
COPII-coated Vesicle Cargo Loading
COPII-coated Vesicle Budding
Negative Regulation Of TORC1 Signaling
Positive Regulation Of TORC1 Signaling
Post-transcriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery
RNA Export From Nucleus
Proteolysis
Protein Import Into Nucleus
Nucleocytoplasmic Transport
Nuclear Pore Organization
Protein Transport
Telomere Tethering At Nuclear Periphery
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of MRNA Splicing, Via Spliceosome
MRNA Transport
Nuclear Pore Complex Assembly
Pathways
ISG15 antiviral mechanism
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
COPII-mediated vesicle transport
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
RHO GTPases Activate Formins
tRNA processing in the nucleus
Mitotic Prometaphase
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
Postmitotic nuclear pore complex (NPC) reformation
Amino acids regulate mTORC1
EML4 and NUDC in mitotic spindle formation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Malaria (
31844061
)
Metabolite levels (Dihydroxy docosatrienoic acid) (
23934736
)
Interacting Genes
14 interacting genes:
ADGRF5
CFAP43
CLDN12
EGFR
HAPLN2
HSPB1
LTB4R2
NUP98
RAB11A
SEC16B
SEC31A
TRAF5
WDR44
WEE2-AS1
19 interacting genes:
APC
CREBBP
CSNK2A1
EP300
HDAC1
IPO5
KPNB1
NUP133
NUP188
NUP205
NUP62
NUP88
NXF1
RAE1
RCC1
SEC13
TNPO1
TNPO2
TPR
Entrez ID
6396
4928
HPRD ID
02538
03012
Ensembl ID
ENSG00000157020
ENSG00000110713
Uniprot IDs
A8MWR8
P55735
A0A8V8TR21
H0YCR0
H0YEN4
P52948
PDB IDs
3BG0
3BG1
5A9Q
7PEQ
7R5J
7R5K
7UHY
1KO6
2Q5X
2Q5Y
3MMY
4OWR
5A9Q
6BZM
7F60
7F90
7MNI
7PEQ
7Q64
7Q65
7Q66
7Q67
7VPG
7VPH
8CI8
Enriched GO Terms of Interacting Partners
?
Regulation Of Protein Kinase C Signaling
Establishment Of Protein Localization
Golgi Vesicle Transport
Cellular Localization
Protein Transport
Endoplasmic Reticulum Exit Site
Golgi To Plasma Membrane Protein Transport
Positive Regulation Of Cilium Assembly
Nuclear Pore
Nuclear Transport
Nucleocytoplasmic Transport
Protein Import Into Nucleus
Import Into Nucleus
Nuclear Envelope
RNA Transport
Structural Constituent Of Nuclear Pore
Protein Localization To Nucleus
MRNA Transport
Nucleobase-containing Compound Transport
Establishment Of Protein Localization To Organelle
RNA Export From Nucleus
Protein Localization To Organelle
Intracellular Transport
Nuclear Export
Intracellular Protein Transport
Protein Transport
Nuclear Localization Sequence Binding
Cellular Localization
Establishment Of Protein Localization
Establishment Of Localization In Cell
MRNA Export From Nucleus
Intracellular Protein Localization
Regulation Of Mitotic Spindle Organization
Nuclear Import Signal Receptor Activity
Regulation Of Microtubule Cytoskeleton Organization
Nucleoplasm
Cytosol
Nuclear Pore Organization
Histone H3K27 Acetyltransferase Activity
Regulation Of Cytoskeleton Organization
Nucleus
Regulation Of Microtubule-based Process
Nuclear Membrane
Regulation Of Mitotic Spindle Assembly
Histone H3K18 Acetyltransferase Activity
N-terminal Peptidyl-lysine Acetylation
Peptide Lactyltransferase (CoA-dependent) Activity
Nuclear Pore Inner Ring
Small GTPase Binding
Regulation Of Cell Cycle
Kinetochore
Ribosomal Protein Import Into Nucleus
RNA Import Into Nucleus
Nucleus Organization
Regulation Of Spindle Assembly
Positive Regulation Of Protein Localization To Nucleus
Regulation Of Cell Cycle Process
Positive Regulation Of Protein Import Into Nucleus
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Tagcloud (Difference)
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Tagcloud (Intersection)
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