CBS and RANBP9

Number of citations of the paper that reports this interaction (PMID 17087506)
11

Data Source:
BioGRID (two hybrid)

		CBS	RANBP9
Gene Name		cystathionine-beta-synthase	RAN binding protein 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytosol Intracellular Membrane-bounded Organelle	Nucleus Cytosol Microtubule Associated Complex
	Molecular Function	Cystathionine Beta-synthase Activity Protein Binding Enzyme Binding Heme Binding Pyridoxal Phosphate Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Modified Amino Acid Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Cysteine Biosynthetic Process From Serine L-serine Metabolic Process L-serine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Transsulfuration L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process Homocysteine Catabolic Process Small Molecule Metabolic Process Homocysteine Metabolic Process Hydrogen Sulfide Biosynthetic Process	Protein Complex Assembly Microtubule Nucleation Axon Guidance
Pathways		Sulfur amino acid metabolism Metabolism of amino acids and derivatives Cysteine formation from homocysteine	Axon guidance L1CAM interactions
Drugs		Pyridoxal Phosphate S-Adenosylmethionine L-Serine L-Cysteine Heme
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Homocysteine levels ( 20031578) Obesity-related traits ( 23251661)	Breast cancer ( 23535729)
Protein-Protein Interactions		20 interactors: CBX4 COL4A3BP DAXX EHHADH FXR2 HGS HID1 HTT PIAS1 PIAS3 PIN1 PRKAG1 PRKAR1A PSMA1 RANBP9 UBASH3A UBE2I UGP2 VTA1 ZDHHC17	51 interactors: ADAP1 ADAP2 APC AR AXL BACE1 BRCA1 CACNA1G CALB1 CBS CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 OPRM1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1
Entrez ID		875	10048
HPRD ID		01994	04835
Ensembl ID		ENSG00000160200	ENSG00000010017
Uniprot IDs		P35520 Q9NTF0	Q96S59
PDB IDs		1JBQ 1M54 4L0D 4L27 4L28 4L3V
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Protein Sumoylation Regulation Of Signaling Cell Cycle Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Sumoylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Endosomal Transport Endoplasmic Reticulum Organization Protein Transport Regulation Of Cell Cycle Peptidyl-amino Acid Modification Neural Plate Formation Response To Brefeldin A Positive Regulation Of SUMO Transferase Activity Establishment Of Protein Localization Viral Process Monocarboxylic Acid Metabolic Process Intracellular Transport Response To Stimulus Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Cell Cycle Process Negative Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity ER To Golgi Ceramide Transport Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Ligase Activity Small Molecule Metabolic Process Mitotic Cell Cycle Process Mesoderm Formation Regulation Of Catalytic Activity Negative Regulation Of Signaling Mesoderm Morphogenesis Organelle Organization Regulation Of Ubiquitin-protein Transferase Activity	Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Organ Development Response To Organic Substance Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Organic Substance Signal Transduction Cellular Response To Organic Cyclic Compound Signaling DNA-templated Transcription, Initiation Cellular Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Response To Stimulus Response To Organic Cyclic Compound Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Tissue Development Response To Lipid Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Response To Growth Factor Epithelium Development Wound Healing Negative Regulation Of Signal Transduction Regulation Of Cell Proliferation Response To Hormone Reproductive Process Regulation Of Intracellular Signal Transduction Apoptotic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cell Activation Negative Regulation Of Signaling DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Tagcloud ?		catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Difference) ?		catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Intersection) ?