CBS and COL4A3BP

Number of citations of the paper that reports this interaction (PMID 19447967)
10

Data Source:
BioGRID (two hybrid)

		CBS	COL4A3BP
Gene Name		cystathionine-beta-synthase	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytosol Intracellular Membrane-bounded Organelle	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Cystathionine Beta-synthase Activity Protein Binding Enzyme Binding Heme Binding Pyridoxal Phosphate Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding Modified Amino Acid Binding	Protein Kinase Activity Protein Binding Ceramide Transporter Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Cysteine Biosynthetic Process From Serine L-serine Metabolic Process L-serine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Transsulfuration L-cysteine Catabolic Process Cellular Nitrogen Compound Metabolic Process Homocysteine Catabolic Process Small Molecule Metabolic Process Homocysteine Metabolic Process Hydrogen Sulfide Biosynthetic Process	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Protein Phosphorylation Sphingolipid Metabolic Process Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Proliferation Sphingolipid Biosynthetic Process Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Small Molecule Metabolic Process Lipid Homeostasis Mitochondrion Morphogenesis
Pathways		Sulfur amino acid metabolism Metabolism of amino acids and derivatives Cysteine formation from homocysteine
Drugs		Pyridoxal Phosphate S-Adenosylmethionine L-Serine L-Cysteine Heme
Diseases
GWAS		Blood trace element (Se levels) ( 23720494) Homocysteine levels ( 20031578) Obesity-related traits ( 23251661)	Quantitative traits ( 19197348)
Protein-Protein Interactions		20 interactors: CBX4 COL4A3BP DAXX EHHADH FXR2 HGS HID1 HTT PIAS1 PIAS3 PIN1 PRKAG1 PRKAR1A PSMA1 RANBP9 UBASH3A UBE2I UGP2 VTA1 ZDHHC17	10 interactors: ACTL8 ARL6IP1 CBS COL4A3 CSNK1G2 ITGB3BP POM121 RTN3 RTN4 TGM2
Entrez ID		875	10087
HPRD ID		01994	05246
Ensembl ID		ENSG00000160200	ENSG00000113163
Uniprot IDs		P35520 Q9NTF0	Q9Y5P4
PDB IDs		1JBQ 1M54 4L0D 4L27 4L28 4L3V	2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Protein Sumoylation Regulation Of Signaling Cell Cycle Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Protein Modification By Small Protein Conjugation Regulation Of Protein Sumoylation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Androgen Receptor Signaling Pathway Regulation Of Protein Ubiquitination Endosomal Transport Endoplasmic Reticulum Organization Protein Transport Regulation Of Cell Cycle Peptidyl-amino Acid Modification Neural Plate Formation Response To Brefeldin A Positive Regulation Of SUMO Transferase Activity Establishment Of Protein Localization Viral Process Monocarboxylic Acid Metabolic Process Intracellular Transport Response To Stimulus Cellular Protein Metabolic Process Positive Regulation Of Catalytic Activity Cell Cycle Process Negative Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Ubiquitin-protein Transferase Activity ER To Golgi Ceramide Transport Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Ligase Activity Small Molecule Metabolic Process Mitotic Cell Cycle Process Mesoderm Formation Regulation Of Catalytic Activity Negative Regulation Of Signaling Mesoderm Morphogenesis Organelle Organization Regulation Of Ubiquitin-protein Transferase Activity	Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Organization Cysteine Biosynthetic Process From Serine Homocysteine Catabolic Process Cysteine Biosynthetic Process Via Cystathionine Apoptotic Process Programmed Cell Death Cell Death Death Endomembrane System Organization Cell Surface Receptor Signaling Pathway Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Transsulfuration Endothelial Cell Apoptotic Process Regulation Of Branching Morphogenesis Of A Nerve Cysteine Biosynthetic Process L-cysteine Catabolic Process Hydrogen Sulfide Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death L-serine Catabolic Process Positive Regulation Of Cell Death Hydrogen Sulfide Metabolic Process Regulation Of Apoptotic Process Salivary Gland Cavitation Regulation Of Cell Death Cysteine Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Neurotrophin Signaling Pathway Homocysteine Metabolic Process
Tagcloud ?		catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose
Tagcloud (Difference) ?		catalyze cerevisiae considerably consumed dehydrogenase fermentation flux insufficient lacks metabolically mixtures oxygenation pentose pichia reductase s103 s104 saccharomyces stipitis tal tal1 tkl1 transaldolase transketolase utilization xyl1 xyl2 xylitol xylose
Tagcloud (Intersection) ?