GPAA1 and LY6E

Data Source: HiPPIP (Novel)

		GPAA1	LY6E
Name		glycosylphosphatidylinositol anchor attachment 1	lymphocyte antigen 6 family member E
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Centrosome Cytosol Membrane GPI-anchor Transamidase Complex	Extracellular Region Plasma Membrane Membrane Synapse Side Of Membrane
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding GPI Anchor Binding	Protein Binding Acetylcholine Receptor Inhibitor Activity Acetylcholine Receptor Binding
	Biological Process	GPI Anchor Biosynthetic Process Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis	Cell Surface Receptor Signaling Pathway Host-mediated Suppression Of Symbiont Invasion Acetylcholine Receptor Signaling Pathway
Pathways		Attachment of GPI anchor to uPAR	Post-translational modification: synthesis of GPI-anchored proteins
GWAS		Asthma ( 31959851 ) Bipolar disorder ( 31043756 ) Bipolar I disorder ( 31043756 ) Serum metabolite concentrations in chronic kidney disease ( 33838163 ) Serum metabolite levels ( 23093944 )	No GWAS studies recorded
Novel Interactors		9 novel interactors: ADAMDEC1 CACNG8 DGAT1 GIT1 LRRC14 LY6E NDRG1 TERF2IP TONSL	8 novel interactors: AKR1B1 EIF3H GLI4 GML GPAA1 HSF1 JRK PIP
Interacting Genes		10 interacting genes: AGTR1 AQP2 EIF3E GNRHR GRIK5 PIGK PIGT PIGU PIN1 PRR13	6 interacting genes: CD247 FCGR2B MFSD6 TMEM140 TMEM19 TRARG1
Entrez ID		8733	4061
HPRD ID		04334	03227
Ensembl ID		ENSG00000197858	ENSG00000160932
Uniprot IDs		O43292	Q16553
PDB IDs		7W72 7WLD 8IMX 8IMY	Not available
GO Terms Enriched among Interactors		GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Attachment Of GPI Anchor To Protein GPI Anchor Binding GPI-anchor Transamidase Activity GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Glycolipid Biosynthetic Process Glycolipid Metabolic Process Phosphatidylinositol Biosynthetic Process Glycerolipid Metabolic Process Phosphatidylinositol Metabolic Process Gamma-tubulin Binding Glycerophospholipid Biosynthetic Process Angiotensin Type I Receptor Activity Cis-trans Isomerase Activity Negative Regulation Of ARF Protein Signal Transduction Membrane Lipid Metabolic Process	IgG Binding