CBLB and PLCG2

  • Number of citations of the paper that reports this interaction (PMID 12093870)
  • 9
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

CBLB

PLCG2

Gene Name Cbl proto-oncogene B, E3 ubiquitin protein ligase phospholipase C, gamma 2 (phosphatidylinositol-specific)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 32 interactors: ARHGEF7 BLNK CRKL CRY1 EGFR FLT3 FYB FYN GLRX3 GORASP2 GRB2 HNRNPK KIT NCK1 NCK2 NEDD4 PIK3R1 PLCG2 RET RNF11 SH3KBP1 SHC1 SORBS3 SPRY2 SYK TGFB1I1 TNFRSF11A UBASH3B UBC VAV1 VAV2 ZAP70 34 interactors: BLK BLNK BTK CBLB CD19 DAPP1 EGFR EPOR ERBB2 FCER1G FLT1 FYN GAB1 GAB2 HCK IRS1 ITK JAK1 JAK2 KDR KHDRBS1 LAT LAT2 LCK LCP2 LIME1 LYN NPM1 PRKD1 SH3BP2 SHC1 SYK TEC ZNF512B
Entrez ID 868 5336
HPRD ID 05136 02570
Ensembl ID ENSG00000114423 ENSG00000197943
Uniprot IDs B3KSS7 Q13191 P16885
PDB IDs 2AK5 2BZ8 2DO6 2J6F 2JNH 2LDR 2OOA 2OOB 3PFV 3VGO 3ZNI 2K2J 2W2W 2W2X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
calm3  ccna2  ccnd3  cdk6  cited1  dems  dok  elk3  fyn  git1  hck  lck  module  modules  nonmodule  p85beta  pdgfra  pib5pa  psd93  ptch2  sam68  sh3kbp1  shc  tgfbr1  tgfbr2  vav2  wilcoxon  yes  zfyve9 
16x10  associations  chrne  comprehensively  dysregulated  escc  esccs  esophageal  fyn  gc  gcs  germline  gnai3  han  itch  map2k1  map2k4  mapk8  observe  pak4  pik3r3  prlr  rank  resampling  rps6kb2  tln1  validate  warranted  wasl 
Tagcloud (Difference) ?
calm3  ccna2  ccnd3  cdk6  cited1  dems  dok  elk3  git1  hck  lck  module  modules  nonmodule  p85beta  pdgfra  pib5pa  psd93  ptch2  sam68  sh3kbp1  shc  tgfbr1  tgfbr2  vav2  wilcoxon  yes  zfyve9 
16x10  associations  chrne  comprehensively  dysregulated  escc  esccs  esophageal  gc  gcs  germline  gnai3  han  itch  map2k1  map2k4  mapk8  observe  pak4  pik3r3  prlr  rank  resampling  rps6kb2  tln1  validate  warranted  wasl 
Tagcloud (Intersection) ?
fyn