TPD52L1 and PAK6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TPD52L1	PAK6
Gene Name		tumor protein D52-like 1	p21 protein (Cdc42/Rac)-activated kinase 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity	Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Apoptotic Signaling Pathway	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction By Phosphorylation Intracellular Signal Transduction
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Axon guidance Activation of Rac Signaling by Robo receptor
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: ABL2 EIF3J GPR135 HDAC1 MAL2 MAP3K5 PAK6 TPD52 TPD52L2 TPD52L3 YAE1D1 YWHAB YWHAZ	13 interactors: AKT1 APP AR CDC42 CDK1 ESR1 MAPK14 MDM2 NEK6 RHOJ SEMA3B SNX2 TPD52L1
Entrez ID		7164	56924
HPRD ID		07236	06426
Ensembl ID		ENSG00000111907	ENSG00000137843
Uniprot IDs		E9PPQ1 F6V707 J3KNE7 Q16890	B3KYB0 G5E9R2 Q9NQU5
PDB IDs			2C30 2ODB 4KS7 4KS8
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Apoptotic Process Signal Transduction By Phosphorylation Regulation Of Cell Death Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Activation Of MAPKK Activity Apoptotic Process Phosphorylation Programmed Cell Death Cell Death Death Regulation Of Mitochondrion Organization Positive Regulation Of MAPK Cascade Leukocyte Activation Immune System Process Regulation Of Cellular Process Positive Regulation Of Signal Transduction Immune Response Defense Response Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Golgi Reassembly Positive Regulation Of Interferon-gamma Secretion Positive Regulation Of Cell Death Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Cell Proliferation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Dephosphorylation Histamine Secretion By Mast Cell Signaling Cell Communication Establishment Of Golgi Localization Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway Bergmann Glial Cell Differentiation Golgi Inheritance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Localization Phosphate-containing Compound Metabolic Process Neurotrophin Signaling Pathway	Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of Gene Expression Programmed Cell Death Peptidyl-serine Phosphorylation Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Regulation Of Protein Kinase Activity Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction ERBB Signaling Pathway Regulation Of Mitotic Cell Cycle Regulation Of Protein Localization Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Intracellular Transport Positive Regulation Of Cell Proliferation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Regulation Of Cell Cycle Process Regulation Of Apoptotic Process Positive Regulation Of Kinase Activity Growth Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Neurotrophin Signaling Pathway Positive Regulation Of Catalytic Activity Cell Cycle Checkpoint Regulation Of Cell Death Signaling Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 ngfrap1 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tra1 trf4 tuba4	19a 19b1 5p apaf1 beclin1 daci exerts favor hep3b hepg2 hsa impedance inc interfere lbh589 mentioned mimicking mir30a mirna mirnas oligonucleotides oncomirs panobinostat periodicals proving qpcr restoring transfecting wiley
Tagcloud (Difference) ?		abcf2 adprtl1 amy2b arhgap4 atp6ap1 axin1 casp4 cox1 cox7b ctsl etv4 lgals3bp mgc35136 mgc5528 mt2a mt3 ngfrap1 p53scv ppia prdx2 psap scgb2a2 smoc2 sptan1 sra1 tax1bp1 tra1 trf4 tuba4	19a 19b1 5p apaf1 beclin1 daci exerts favor hep3b hepg2 hsa impedance inc interfere lbh589 mentioned mimicking mir30a mirna mirnas oligonucleotides oncomirs panobinostat periodicals proving qpcr restoring transfecting wiley
Tagcloud (Intersection) ?