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RUNX1T1 and LPXN
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid, two hybrid)
RUNX1T1
LPXN
Description
RUNX1 partner transcriptional co-repressor 1
leupaxin
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nuclear Matrix
Podosome
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Focal Adhesion
Membrane
Nuclear Speck
Cell Projection
Perinuclear Region Of Cytoplasm
Anchoring Junction
Molecular Function
DNA Binding
Transcription Corepressor Activity
Protein Binding
Zinc Ion Binding
Metal Ion Binding
DNA-binding Transcription Factor Binding
Transcription Coregulator Activity
Protein Binding
Metal Ion Binding
Biological Process
DNA-templated Transcription
Negative Regulation Of Fat Cell Differentiation
Negative Regulation Of DNA-templated Transcription
Cell Adhesion
Negative Regulation Of Cell Adhesion
Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cell Adhesion Mediated By Integrin
Substrate Adhesion-dependent Cell Spreading
Endothelial Cell Migration
Negative Regulation Of B Cell Receptor Signaling Pathway
Protein-containing Complex Assembly
Pathways
Drugs
Diseases
Acute myeloid leukemia (AML)
GWAS
Adult body size (
32376654
)
Chronotype (
30696823
)
General risk tolerance (MTAG) (
30643258
)
Heel bone mineral density (
30598549
)
Intelligence (MTAG) (
29326435
)
Number of sexual partners (
30643258
)
Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder (
26184070
)
Plasma anti-thyroglobulin levels (
29678681
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking initiation (
30617275
33082346
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Inflammatory bowel disease (
23128233
)
Lymphoma (
23349640
)
Pulse pressure (
30578418
)
Ulcerative colitis (
28067908
)
Interacting Genes
99 interacting genes:
ABI3
ADAMTSL4
ARHGAP9
ATN1
BCL6
BIRC2
BRCA1
BRME1
CBFA2T3
CBY2
CCDC197
CDC23
CDR2
CEP170P1
CEP83
COG6
CPSF7
CREB3L1
DEUP1
DNMT1
EFHC2
EPS8
ETS1
FAM136A
FAM9A
GFI1
GSE1
HDAC1
HDAC3
HDAC8
HOMER3
HOXB2
HSP90AA1
ID1
ID3
IHO1
KIAA0408
KIFC3
KPNA1
KPNB1
KRT23
KRT27
KRT33B
KRT35
KRTAP13-3
KRTAP19-6
KRTAP6-2
KRTAP6-3
LHX3
LPXN
LZTS1
LZTS2
MEOX2
MID2
NCOR1
NCOR2
NECAB2
NEUROG1
OIP5
PCBD2
PIAS2
PLSCR3
PRDM16
PRDM6
PRKAR1B
PRKAR2A
RAD54L2
REL
RNF4
RTN4IP1
SH3RF1
SIN3A
SORBS3
SPEN
SPRY2
STX11
SYCE1
TAF9B
TAL2
TCF12
TCF3
TCF4
TEKT1
TFIP11
TRIM42
TRIM54
UBQLN4
VDR
VPS52
WBP11
XIAP
ZBTB16
ZFP36
ZFP90
ZMAT1
ZMYM4
ZNF343
ZNF652
ZNF655
33 interacting genes:
AGXT
AQP1
GIT1
HDAC6
HOXA1
HOXC9
IKBKG
IMP3
ITGA4
LIMS1
LMO1
LMO3
MAP2K7
MAPK6
NDN
NR3C1
PHF21A
PLEKHH2
PLEKHN1
PLSCR4
POM121
PTK2
PTK2B
PTPN12
RNF214
RUNX1T1
SFI1
TGFB1
TNS2
TXLNB
VCL
ZNF175
ZNF426
Entrez ID
862
9404
HPRD ID
00590
05651
Ensembl ID
ENSG00000079102
ENSG00000110031
Uniprot IDs
A0A0A0MSU1
B2R6I9
E5RH72
Q06455
W8FW32
B7Z5P7
O60711
PDB IDs
1WQ6
2DJ8
2H7B
2KNH
2KYG
2OD1
2ODD
2PP4
4JOL
1X3H
4XEF
4XEK
4XEV
Enriched GO Terms of Interacting Partners
?
Transcription Repressor Complex
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Protein Binding
Regulation Of Transcription By RNA Polymerase II
Transcription Corepressor Activity
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
DNA Binding
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of RNA Metabolic Process
Heterochromatin Formation
Regulation Of Primary Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Protein Decrotonylase Activity
Histone Decrotonylase Activity
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Androgen Receptor Signaling Pathway
Transcription Cis-regulatory Region Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Intermediate Filament
Histone Deacetylase Complex
Regulation Of Apoptotic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Programmed Cell Death
Zinc Ion Binding
Transcription Corepressor Binding
Chromatin
Positive Regulation Of Neuron Differentiation
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of Metabolic Process
E-box Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Histone Deacetylase Activity, Hydrolytic Mechanism
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Factor Activity
Epigenetic Regulation Of Gene Expression
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Regulation Of Androgen Receptor Signaling Pathway
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Response To Dexamethasone
Focal Adhesion
Positive Regulation Of Fibroblast Migration
Developmental Growth
Developmental Growth Involved In Morphogenesis
Anchoring Junction
Cellular Response To Dexamethasone Stimulus
Cellular Response To Lipid
Cellular Response To Oxygen-containing Compound
Multicellular Organismal-level Homeostasis
Positive Regulation Of Mononuclear Cell Migration
Regulation Of Fibroblast Migration
Response To Fluid Shear Stress
Developmental Cell Growth
Response To Lipid
Signal Complex Assembly
Regulation Of Cell-matrix Adhesion
Response To Glucocorticoid
Regulation Of Fat Cell Differentiation
Cellular Response To Glucocorticoid Stimulus
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Mononuclear Cell Migration
Positive Regulation Of Leukocyte Migration
Cellular Response To Growth Factor Stimulus
Response To Corticosteroid
Regulation Of RNA Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Epidermal Growth Factor Receptor Signaling Pathway
Cellular Response To Corticosteroid Stimulus
Anatomical Structure Morphogenesis
Regulation Of DNA-templated Transcription
Regulation Of Focal Adhesion Assembly
Regulation Of RNA Biosynthetic Process
Response To Growth Factor
Response To Transforming Growth Factor Beta
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
ERBB Signaling Pathway
Regulation Of Cell-substrate Junction Organization
MAP Kinase Activity
Regulation Of Primary Metabolic Process
Regulation Of Cytoskeleton Organization
Cellular Response To Steroid Hormone Stimulus
Nucleus
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Neuron Projection Extension
Positive Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Cell Migration
Positive Regulation Of Catabolic Process
Response To Wounding
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