RUNX1T1 and TAF9B

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RUNX1T1	TAF9B
Description		RUNX1 partner transcriptional co-repressor 1	TATA-box binding protein associated factor 9b
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Matrix	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Transcription Corepressor Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription Negative Regulation Of Fat Cell Differentiation Negative Regulation Of DNA-templated Transcription	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Initiation Transcription By RNA Polymerase II Positive Regulation Of Cell Growth Negative Regulation Of Apoptotic Process Protein Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases		Acute myeloid leukemia (AML)
GWAS		Adult body size ( 32376654) Chronotype ( 30696823) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Number of sexual partners ( 30643258) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Plasma anti-thyroglobulin levels ( 29678681) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258)	Potassium levels ( 29403010)
Interacting Genes		99 interacting genes: ABI3 ADAMTSL4 ARHGAP9 ATN1 BCL6 BIRC2 BRCA1 BRME1 CBFA2T3 CBY2 CCDC197 CDC23 CDR2 CEP170P1 CEP83 COG6 CPSF7 CREB3L1 DEUP1 DNMT1 EFHC2 EPS8 ETS1 FAM136A FAM9A GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HOXB2 HSP90AA1 ID1 ID3 IHO1 KIAA0408 KIFC3 KPNA1 KPNB1 KRT23 KRT27 KRT33B KRT35 KRTAP13-3 KRTAP19-6 KRTAP6-2 KRTAP6-3 LHX3 LPXN LZTS1 LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 OIP5 PCBD2 PIAS2 PLSCR3 PRDM16 PRDM6 PRKAR1B PRKAR2A RAD54L2 REL RNF4 RTN4IP1 SH3RF1 SIN3A SORBS3 SPEN SPRY2 STX11 SYCE1 TAF9B TAL2 TCF12 TCF3 TCF4 TEKT1 TFIP11 TRIM42 TRIM54 UBQLN4 VDR VPS52 WBP11 XIAP ZBTB16 ZFP36 ZFP90 ZMAT1 ZMYM4 ZNF343 ZNF652 ZNF655	8 interacting genes: APP DRAP1 FBXO7 H3-4 RUNX1T1 SS18L1 TP53 TRIM15
Entrez ID		862	51616
HPRD ID		00590	06739
Ensembl ID		ENSG00000079102	ENSG00000187325
Uniprot IDs		A0A0A0MSU1 B2R6I9 E5RH72 Q06455 W8FW32	Q9HBM6
PDB IDs		1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL	7KTR 7KTS
Enriched GO Terms of Interacting Partners?		Transcription Repressor Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Transcription By RNA Polymerase II Transcription Corepressor Activity Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Heterochromatin Formation Regulation Of Primary Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Protein Decrotonylase Activity Histone Decrotonylase Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Negative Regulation Of Androgen Receptor Signaling Pathway Transcription Cis-regulatory Region Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Intermediate Filament Histone Deacetylase Complex Regulation Of Apoptotic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Programmed Cell Death Zinc Ion Binding Transcription Corepressor Binding Chromatin Positive Regulation Of Neuron Differentiation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Metabolic Process E-box Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Histone Deacetylase Activity, Hydrolytic Mechanism Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Epigenetic Regulation Of Gene Expression DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Nucleobase-containing Compound Metabolic Process	Protein Heterodimerization Activity Regulation Of Cell Differentiation Core Promoter Sequence-specific DNA Binding Molecular Function Activator Activity Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Gene Expression, Epigenetic Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Neuron Apoptotic Process Chromatin Organization Regulation Of Developmental Process Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Regulation Of Carbohydrate Catabolic Process Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Dendrite Development Nucleus Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitophagy Negative Regulation Of Helicase Activity Regulation Of Autophagy Of Mitochondrion Negative Regulation Of G1 To G0 Transition Negative Regulation Of Cell Cycle G1/S Phase Transition Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Autophagy Of Mitochondrion Regulation Of MiRNA Transcription Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import DNA Binding Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of DNA-templated Transcription Regulation Of MiRNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Purine Nucleotide Metabolic Process Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Regulation Of Mitotic Cell Cycle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
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