TCAP and MYOZ1

Number of citations of the paper that reports this interaction (PMID 10984498)
27

Data Source:
HPRD (in vitro)

		TCAP	MYOZ1
Gene Name		titin-cap	myozenin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Z Disc I Band	Nucleus Actin Cytoskeleton Pseudopodium
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein Binding, Bridging Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding	Protein Binding FATZ Binding
	Biological Process	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Protein Complex Assembly Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction	Myofibril Assembly
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: ANKRD2 ATXN1 FAS FYN MDM2 MSTN MYOZ1 MYOZ3 PDPK1 RELA SIVA1 TRIM55 TRIM63 TTN	13 interactors: ACTN1 ACTN2 ACTN4 APP BRCA1 FLNC LDB3 MAGEA11 PNKP PRKAA2 TCAP TRIM55 TRIM63
Entrez ID		8557	58529
HPRD ID		05133	05725
Ensembl ID			ENSG00000177791
Uniprot IDs		A2TDC0 O15273	B4DUK4 Q9NP98
PDB IDs		1YA5 2F8V
Enriched GO Terms of Interacting Partners?		Response To Abiotic Stimulus Response To Hormone Cellular Response To Hormone Stimulus Response To Steroid Hormone Skeletal Muscle Atrophy Response To Mechanical Stimulus Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Striated Muscle Atrophy Activation-induced Cell Death Of T Cells Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Cell Death Muscle Atrophy Cellular Response To Growth Factor Stimulus Muscle System Process Response To Growth Factor Skeletal Muscle Adaptation Fc Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Organic Substance Extrinsic Apoptotic Signaling Pathway Regulation Of Signal Transduction Response To Stimulus T Cell Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Apoptotic Process Organ Development Cellular Response To Organic Cyclic Compound Phosphatidylinositol-mediated Signaling Antigen Receptor-mediated Signaling Pathway Regulation Of Signaling Response To Lipid Regulation Of Protein Metabolic Process Cellular Response To Lipid Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Response To Peptide Hormone Negative Regulation Of Apoptotic Process Signaling Response To Glucocorticoid Negative Regulation Of Programmed Cell Death Cellular Response To Organonitrogen Compound Epidermal Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Cell Communication Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Inorganic Substance	Platelet Degranulation Protein Localization To Tight Junction Platelet Activation Cell Junction Assembly Protein Localization To Cell Junction Response To Abiotic Stimulus Actin Filament-based Process Cellular Component Assembly Exocytosis Actin Crosslink Formation Blood Coagulation Hemostasis Response To Stress Striated Muscle Cell Development Muscle Cell Development Secretion By Cell Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Intracellular Receptor Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Cytoskeleton Organization Cell-cell Junction Organization Regulation Of Body Fluid Levels Muscle Contraction Actin Cytoskeleton Organization Wound Healing Striated Muscle Cell Differentiation Secretion Actin-mediated Cell Contraction Tight Junction Assembly Adherens Junction Assembly Muscle System Process Cell Activation Muscle Fiber Development Response To Wounding Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Sarcomere Organization Positive Regulation Of Transporter Activity Actin Filament Organization Actin Filament Bundle Assembly Actin Filament-based Movement Regulation Of Apoptotic Process Muscle Cell Differentiation Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Apical Junction Assembly Regulation Of Cell Death Positive Regulation Of Ion Transmembrane Transport
Tagcloud ?		allegedly catalysis conformationally coordinating crd dichotomy e147 inactivity invertebrate m34 mechanosensing murf1 murf2 myofibril myofibrillogenesis myofilament pseudokinase pseudokinases releases sarcomeric sterically stretch striated titin tk transfers translates trophicity unfolding	adapt calcineurin calsarcin calsarcins changing demands disc distances enable fast fiber fibers ko modulates muscles myoblasts myopathic myozenin nfat organism overt rcan1 running sarcomeric skeletal slow striated tightly twitch
Tagcloud (Difference) ?		allegedly catalysis conformationally coordinating crd dichotomy e147 inactivity invertebrate m34 mechanosensing murf1 murf2 myofibril myofibrillogenesis myofilament pseudokinase pseudokinases releases sterically stretch titin tk transfers translates trophicity unfolding	adapt calcineurin calsarcin calsarcins changing demands disc distances enable fast fiber fibers ko modulates muscles myoblasts myopathic myozenin nfat organism overt rcan1 running skeletal slow tightly twitch
Tagcloud (Intersection) ?		sarcomeric striated