CAST and HTRA1

  • Number of citations of the paper that reports this interaction (PubMedID 15101818)
  • 30
  • Data Source:
  • HPRD (two hybrid)

CAST

HTRA1

Description calpastatin HtrA serine peptidase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Alcohol dependence ( 19581569)
  • Appendicular lean mass ( 33097823)
  • Body mass index ( 26426971 29381148)
  • Fish- and plant-related diet ( 32066663)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Advanced age-related macular degeneration ( 26691988)
  • Age-related macular degeneration ( 20385819 20385826 20861866 21665990 22694956 32741009 23326517 23455636 23536807)
  • Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
  • Age-related macular degeneration (CNV vs. GA) ( 22705344)
  • Age-related macular degeneration (extreme sampling) ( 23577725)
  • Age-related macular degeneration (geographic atrophy) ( 22705344)
  • Age-related macular degeneration (MTAG) ( 32277175)
  • Age-related macular degeneration (wet) ( 17053108)
  • Coronary artery disease ( 33020668 29212778)
  • Disease progression in age-related macular degeneration ( 29346644)
  • Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
  • Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
  • Diverticular disease ( 30177863)
  • Early age-related macular degeneration ( 32843070)
  • Exudative age-related macular degeneration ( 25629512)
  • Laterality in neovascular age-related macular degeneration ( 28775256)
  • Lung function (FEV1/FVC) ( 30804560 30061609)
  • Migraine ( 27322543)
  • Myocardial infarction ( 33532862)
  • Neovascular age-related macular degeneration ( 28703135)
  • Refractive error ( 32231278)
  • Systolic blood pressure ( 30578418 30224653)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
Interacting Genes 11 interacting genes: CAPN1 CAPNS1 CASP1 CASP3 CASP7 HTRA1 PPFIA1 PPFIA2 PPFIA3 PPFIA4 SUMO2 22 interacting genes: APOE BMP4 CAST CDYL COL1A1 COL2A1 COL3A1 COX5A CSNK2B FAM107A FCHSD2 GDF5 GOLGA2 IMPDH1 LRP10 LTBP1 MAPT NOS3 PARD6B RPS6KA1 TENT5A XIAP
Entrez ID 831 5654
HPRD ID 00233 03725
Ensembl ID ENSG00000310517 ENSG00000166033
Uniprot IDs A0A6Q8PH20 B7Z6N0 E9PCH5 E9PDE4 P20810 Q59HE3 Q86YM9 Q92743
PDB IDs 2JOA 2YTW 3NUM 3NWU 3NZI 3TJN 3TJO 3TJQ 6Z0E 6Z0X 6Z0Y 7SJN 7SJO 7SJP 8SDM 8SDP 8SE7 8SE8
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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