| Description | calpastatin | HtrA serine peptidase 1 | 
    
      | Image | No pdb structure |  | 
    
 
     | Cellular Component |  |  | 
    
      | Molecular Function |  |  | 
    
      | Biological Process |  |  | 
    
      | Pathways |  |  | 
    
      | Drugs |  |  | 
    
      | Diseases |  |  | 
    
      | GWAS | 
                          Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)Alcohol dependence ( 19581569)Appendicular lean mass ( 33097823)Body mass index ( 26426971 29381148)Fish- and plant-related diet ( 32066663)Medication use (agents acting on the renin-angiotensin system) ( 31015401) | 
                          Advanced age-related macular degeneration ( 26691988)Age-related macular degeneration ( 20385819 20385826 20861866 21665990 22694956 32741009 23326517 23455636 23536807)Age-related macular degeneration (choroidal neovascularisation) ( 22705344)Age-related macular degeneration (CNV vs. GA) ( 22705344)Age-related macular degeneration (extreme sampling) ( 23577725)Age-related macular degeneration (geographic atrophy) ( 22705344)Age-related macular degeneration (MTAG) ( 32277175)Age-related macular degeneration (wet) ( 17053108)Coronary artery disease ( 33020668 29212778)Disease progression in age-related macular degeneration ( 29346644)Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)Diverticular disease ( 30177863)Early age-related macular degeneration ( 32843070)Exudative age-related macular degeneration ( 25629512)Laterality in neovascular age-related macular degeneration ( 28775256)Lung function (FEV1/FVC) ( 30804560 30061609)Migraine ( 27322543)Myocardial infarction ( 33532862)Neovascular age-related macular degeneration ( 28703135)Refractive error ( 32231278)Systolic blood pressure ( 30578418 30224653)White matter hyperintensity volume ( 33293549)White matter hyperintensity volume (adjusted for hypertension) ( 33293549) | 
    
	
    
				
    
      | Interacting Genes | 11 interacting genes:
                  CAPN1
                  CAPNS1
                  CASP1
                  CASP3
                  CASP7
                  HTRA1
                  PPFIA1
                  PPFIA2
                  PPFIA3
                  PPFIA4
                  SUMO2 | 22 interacting genes:
                  APOE
                  BMP4
                  CAST
                  CDYL
                  COL1A1
                  COL2A1
                  COL3A1
                  COX5A
                  CSNK2B
                  FAM107A
                  FCHSD2
                  GDF5
                  GOLGA2
                  IMPDH1
                  LRP10
                  LTBP1
                  MAPT
                  NOS3
                  PARD6B
                  RPS6KA1
                  TENT5A
                  XIAP | 
				
    
      | Entrez ID | 831 | 5654 | 
    
      | HPRD ID | 00233 | 03725 | 
    
      | Ensembl ID | ENSG00000310517 | ENSG00000166033 | 
    
      | Uniprot IDs | A0A6Q8PH20 
                B7Z6N0 
                E9PCH5 
                E9PDE4 
                P20810 
                Q59HE3 
                Q86YM9 | Q92743 | 
    
      | PDB IDs |  | 2JOA 
                    2YTW 
                    3NUM 
                    3NWU 
                    3NZI 
                    3TJN 
                    3TJO 
                    3TJQ 
                    6Z0E 
                    6Z0X 
                    6Z0Y 
                    7SJN 
                    7SJO 
                    7SJP 
                    8SDM 
                    8SDP 
                    8SE7 
                    8SE8 | 
    
      | Enriched GO Terms of Interacting Partners? |  |  | 
    
      | Tagcloud ? |  |  | 
    
      | Tagcloud (Difference) ? |  |  | 
    
      | Tagcloud (Intersection) ? |  |