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DGKD and MYH2
Number of citations of the paper that reports this interaction (PMID
10082674
)
6
Data Source:
HPRD
(in vitro)
DGKD
MYH2
Gene Name
diacylglycerol kinase, delta 130kDa
myosin, heavy chain 2, skeletal muscle, adult
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Cytoplasmic Membrane-bounded Vesicle
Golgi Apparatus
Actomyosin Contractile Ring
Cytosol
Muscle Myosin Complex
Cell-cell Junction
Myofibril
Sarcomere
A Band
Myosin Filament
Protein Complex
Molecular Function
NAD+ Kinase Activity
Diacylglycerol Kinase Activity
Protein Binding
ATP Binding
Diacylglycerol Binding
Protein Homodimerization Activity
Metal Ion Binding
Protein Heterodimerization Activity
Microfilament Motor Activity
Actin Binding
Protein Binding
Calmodulin Binding
ATP Binding
Biological Process
Endocytosis
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Multicellular Organismal Development
Blood Coagulation
Response To Organic Substance
Protein Transport
Cell Growth
Phosphorylation
Second-messenger-mediated Signaling
Platelet Activation
Diacylglycerol Metabolic Process
Protein Homooligomerization
Plasma Membrane Repair
Muscle Contraction
Metabolic Process
Response To Activity
Muscle Filament Sliding
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Membrane Organization
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Platelet activation, signaling and aggregation
Effects of PIP2 hydrolysis
Translocation of GLUT4 to the plasma membrane
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
Drugs
Diseases
GWAS
Bilirubin levels (
20639394
)
Calcium levels (
20705733
)
Crohn's disease (
22412388
)
Protein-Protein Interactions
7 interactors:
DGKH
HAX1
IGSF21
MYH2
PRKCA
SREK1
TNFRSF14
6 interactors:
AMPD1
DGKD
OBSCN
PRKCE
PTK2B
S100A4
Entrez ID
8527
4620
HPRD ID
03492
01173
Ensembl ID
ENSG00000077044
ENSG00000125414
Uniprot IDs
Q16760
Q567P6
Q9UKX2
PDB IDs
1R79
3BQ7
Enriched GO Terms of Interacting Partners
?
Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Immune System Process
Positive Regulation Of Myeloid Leukocyte Differentiation
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Immune System Process
Positive Regulation Of Myeloid Cell Differentiation
Regulation Of Cellular Ketone Metabolic Process
Positive Regulation Of Dense Core Granule Biogenesis
Wound Healing
Regulation Of Myeloid Leukocyte Differentiation
Regulation Of Protein Transport
Regulation Of Establishment Of Protein Localization
Response To Wounding
Histone H3-T6 Phosphorylation
Response To Cytokine
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Protein Localization
Regulation Of Myeloid Cell Differentiation
Positive Regulation Of Phosphorylation
Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Cytokine Secretion Involved In Immune Response
Platelet Activation
Positive Regulation Of Protein Modification Process
Regulation Of Cellular Localization
Regulation Of Protein Phosphorylation
Peptidyl-serine Autophosphorylation
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of Alpha-beta T Cell Proliferation
Plasma Membrane Repair
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Granulocyte Differentiation
Desmosome Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Mitochondrion Degradation
Negative Regulation Of Glucose Import
Positive Regulation Of Cell Migration
Immune Response
Positive Regulation Of Cell Motility
Regulation Of Phosphorylation
Positive Regulation Of Macrophage Differentiation
Regulation Of Cytokine Secretion Involved In Immune Response
Positive Regulation Of Cellular Component Movement
Defense Response
Desmosome Organization
Positive Regulation Of Locomotion
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Response To Organic Substance
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Epithelial Cell Migration
Response To Ammonium Ion
Negative Regulation Of Ion Transport
Positive Regulation Of Cellular Glucuronidation
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Synaptic Transmission
Actomyosin Structure Organization
Regulation Of Receptor Activity
Positive Regulation Of Cell-substrate Adhesion
Positive Regulation Of Protein Polymerization
Regulation Of Intracellular Signal Transduction
Cell Activation
Regulation Of CGMP-mediated Signaling
Marginal Zone B Cell Differentiation
Positive Regulation Of B Cell Chemotaxis
TRAM-dependent Toll-like Receptor 4 Signaling Pathway
Phosphorylation
Response To Ethanol
Intracellular Signal Transduction
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Epithelial Cell Migration
Response To Alkaloid
Regulation Of Transmembrane Transporter Activity
Regulation Of Carbohydrate Metabolic Process
Leukocyte Activation Involved In Immune Response
Positive Regulation Of Cytosolic Calcium Ion Concentration
Regulation Of Ion Homeostasis
Positive Regulation Of Intracellular Signal Transduction
Protein Localization To M-band
Positive Regulation Of Protein Complex Assembly
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Actin Filament Polymerization
Cytosolic Calcium Ion Homeostasis
Activation Of Janus Kinase Activity
Platelet Activation
Regulation Of Cell-substrate Adhesion
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Regulation Of Peptidyl-tyrosine Phosphorylation
Neurotrophin TRK Receptor Signaling Pathway
Apoptotic Process
Neurotrophin Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud
?
breakpoint
breaks
coliai
cryb1
d17s1
d17s19
d17s6
d17z
erba1
gaa
galk
gcsf
ghc
hox2
hybrids
isoenzymes
mpo
myh1
ngfr
ngl
probes
pter
qter
regionally
rnp2
rnu2
tk1
transfectant
um
Tagcloud (Difference)
?
breakpoint
breaks
coliai
cryb1
d17s1
d17s19
d17s6
d17z
erba1
gaa
galk
gcsf
ghc
hox2
hybrids
isoenzymes
mpo
myh1
ngfr
ngl
probes
pter
qter
regionally
rnp2
rnu2
tk1
transfectant
um
Tagcloud (Intersection)
?