MYH2 and DUX4L9

Number of citations of the paper that reports this interaction (PubMedID 26816005)
133

Data Source:
BioGRID (two hybrid)

		MYH2	DUX4L9
Description		myosin heavy chain 2	double homeobox 4 like 9 (pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Muscle Myosin Complex Cell-cell Junction Myosin Complex Myosin II Complex Myofibril Sarcomere Myosin Filament Protein-containing Complex Supramolecular Fiber
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Actin Filament Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding
Pathways		Regulation of actin dynamics for phagocytic cup formation FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: AMPD1 DGKD DUX4L9 OBSCN PRKCE PTK2B S100A4	10 interacting genes: ACTA1 ACTN3 FHL3 MSS51 MYH2 NDUFB10 RBM24 RPL4 SF1 VDAC2
Entrez ID		4620	100288711
HPRD ID		01173
Ensembl ID		ENSG00000125414	ENSG00000224807
Uniprot IDs		Q9UKX2
PDB IDs
Enriched GO Terms of Interacting Partners?		Signaling Receptor Activator Activity Kinase Activity AMP Deaminase Activity Phosphate-containing Compound Metabolic Process ATP Binding Positive Regulation Of Protein Polymerization Regulation Of Actin Filament Polymerization Neurotransmitter Receptor Regulator Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of B Cell Chemotaxis Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Actin Filament Polymerization Negative Regulation Of Monoatomic Ion Transport Phosphorylation Protein Kinase Activity Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-substrate Adhesion TRAM-dependent Toll-like Receptor 4 Signaling Pathway Ethanol Binding Negative Regulation Of Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Clathrin-dependent Endocytosis Protein Localization To M-band Regulation Of Actin Polymerization Or Depolymerization Regulation Of Calcium Ion Transmembrane Transport Cell Activation Involved In Immune Response Regulation Of Actin Filament Length Leukocyte Activation Involved In Immune Response Positive Regulation Of Synaptic Transmission Cell Activation Activation Of Janus Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Toxin Catabolic Process IMP Salvage GMP Salvage Perinuclear Region Of Cytoplasm Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Signal Transduction Positive Regulation Of Mucus Secretion Positive Regulation Of Cytoskeleton Organization Diacylglycerol Catabolic Process Deaminase Activity NMDA Selective Glutamate Receptor Complex Transferase Activity Signal Complex Assembly Positive Regulation Of Cell Communication Regulation Of Signal Transduction Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Signaling Regulation Of Cell-substrate Adhesion Regulation Of Calcium Ion Transport	Sarcomere Actin Filament Muscle System Process Stress Fiber Regulation Of Myotube Differentiation Actin Binding Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Muscle Cell Differentiation Muscle Cell Development Actin Filament-based Process Positive Regulation Of Bone Mineralization Involved In Bone Maturation Focal Adhesion Positive Regulation Of Skeletal Muscle Fiber Differentiation Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Negative Regulation Of Relaxation Of Muscle Regulation Of Muscle Cell Differentiation Response To Denervation Involved In Regulation Of Muscle Adaptation Positive Regulation Of Skeletal Muscle Tissue Growth Transition Between Fast And Slow Fiber Regulation Of Skeletal Muscle Tissue Growth Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Z Disc Porin Activity Voltage-gated Monoatomic Anion Channel Activity U2AF Complex MRNA 3'-splice Site Recognition Positive Regulation Of 3'-UTR-mediated MRNA Stabilization MRNA CDS Binding Regulation Of Skeletal Muscle Fiber Differentiation Striated Muscle Thin Filament Muscle Atrophy Response To Muscle Inactivity Positive Regulation Of Skeletal Muscle Fiber Development Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Ribosome Ceramide Binding Mitochondrial Outer Membrane Permeabilization Negative Regulation Of Cytoplasmic Translation Positive Regulation Of Skeletal Muscle Cell Differentiation Muscle Contraction Regulation Of Skeletal Muscle Fiber Development Actin Filament Binding
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