MYH2 and S100A4

Number of citations of the paper that reports this interaction (PMID 12756252)
24

Data Source:
HPRD (in vivo, in vitro)

		MYH2	S100A4
Gene Name		myosin, heavy chain 2, skeletal muscle, adult	S100 calcium binding protein A4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Actomyosin Contractile Ring Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere A Band Myosin Filament Protein Complex	Extracellular Space Nucleus Neuron Projection Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding	Actin Binding Calcium Ion Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding Calcium-dependent Protein Binding RAGE Receptor Binding
	Biological Process	Plasma Membrane Repair Muscle Contraction Metabolic Process Response To Activity Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Membrane Organization	Epithelial To Mesenchymal Transition Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Translocation of GLUT4 to the plasma membrane Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AMPD1 DGKD OBSCN PRKCE PTK2B S100A4	22 interactors: ACTA1 ANXA2 BAG6 MDM2 METAP2 MYH10 MYH2 MYH4 MYH9 NOV PPFIBP1 S100A1 S100B S100P SEPT2 SEPT6 SEPT7 SMAD3 TP53 TPM2 TPM3 UNC119
Entrez ID		4620	6275
HPRD ID		01173	15914
Ensembl ID		ENSG00000125414	ENSG00000196154
Uniprot IDs		Q567P6 Q9UKX2	P26447
PDB IDs			1M31 2LNK 2Q91 3C1V 3CGA 3KO0 3M0W 3ZWH 4ETO 4HSZ
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To Organic Substance Phosphate-containing Compound Metabolic Process Positive Regulation Of Epithelial Cell Migration Response To Ammonium Ion Negative Regulation Of Ion Transport Positive Regulation Of Cellular Glucuronidation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Transmission Actomyosin Structure Organization Regulation Of Receptor Activity Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Polymerization Regulation Of Intracellular Signal Transduction Cell Activation Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis TRAM-dependent Toll-like Receptor 4 Signaling Pathway Phosphorylation Response To Ethanol Intracellular Signal Transduction Regulation Of Ion Transmembrane Transporter Activity Regulation Of Epithelial Cell Migration Response To Alkaloid Regulation Of Transmembrane Transporter Activity Regulation Of Carbohydrate Metabolic Process Leukocyte Activation Involved In Immune Response Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Positive Regulation Of Intracellular Signal Transduction Protein Localization To M-band Positive Regulation Of Protein Complex Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Actin Filament Polymerization Cytosolic Calcium Ion Homeostasis Activation Of Janus Kinase Activity Platelet Activation Regulation Of Cell-substrate Adhesion Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Apoptotic Process Neurotrophin Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Actin Filament-based Movement Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Cell Cycle Process Cytokinesis Cell Cycle Actin Filament-based Process Muscle Contraction Cell Division Movement Of Cell Or Subcellular Component Muscle System Process Regulation Of Cell Shape Plasma Membrane Repair Response To External Stimulus Anatomical Structure Morphogenesis Cellular Component Assembly Anatomical Structure Formation Involved In Morphogenesis Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Response To Abiotic Stimulus Mitotic Cell Cycle Regulation Of Cell Morphogenesis Cellular Response To Light Stimulus Cell Projection Morphogenesis Membrane Organization Cell Part Morphogenesis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cell Development Response To Hypoxia Cellular Response To Oxygen Levels Actomyosin Structure Organization Signal Transduction By P53 Class Mediator Wound Healing Response To Light Stimulus Response To Stimulus Regulation Of Protein Stability Cellular Response To Radiation Cell Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To Wounding Cell Differentiation Anatomical Structure Development Immune System Process Cellular Response To Stimulus System Development Cell Projection Organization Positive Regulation Of Transport Cell Adhesion
Tagcloud ?		breakpoint breaks coliai cryb1 d17s1 d17s19 d17s6 d17z erba1 gaa galk gcsf ghc hox2 hybrids isoenzymes mpo myh1 ngfr ngl probes pter qter regionally rnp2 rnu2 tk1 transfectant um	aldh1 anatomically area areas biomarkers cadherin cd44 central detailed egfr expressions fgfr1 heterogeneous immunohistochemical lymph metastatic molecules node nodes peripheral precise prediction recurrence relationships shorter sox2 squamous staining vegfr2
Tagcloud (Difference) ?		breakpoint breaks coliai cryb1 d17s1 d17s19 d17s6 d17z erba1 gaa galk gcsf ghc hox2 hybrids isoenzymes mpo myh1 ngfr ngl probes pter qter regionally rnp2 rnu2 tk1 transfectant um	aldh1 anatomically area areas biomarkers cadherin cd44 central detailed egfr expressions fgfr1 heterogeneous immunohistochemical lymph metastatic molecules node nodes peripheral precise prediction recurrence relationships shorter sox2 squamous staining vegfr2
Tagcloud (Intersection) ?