SF3A1 and DDX42

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		SF3A1	DDX42
Gene Name		splicing factor 3a, subunit 1, 120kDa	DEAD (Asp-Glu-Ala-Asp) box helicase 42
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cajal Body Membrane Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding	Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	Protein Localization Metabolic Process
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 UBC WBP4 WDR77	10 interactors: APP DHX15 FBXO25 PRPF19 RECQL5 SF3A1 SF3B4 SNRPC U2SURP UBC
Entrez ID		10291	11325
HPRD ID		06903	09909
Ensembl ID		ENSG00000099995	ENSG00000198231
Uniprot IDs		E9PAW1 Q15459	Q86XP3
PDB IDs		1ZKH 2DT6 2DT7
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing RNA Metabolic Process MRNA Metabolic Process MRNA 3'-splice Site Recognition Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splice Site Selection Cellular Macromolecular Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Spliceosomal Complex Assembly Negative Regulation Of Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cell Cycle Arrest Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Cell Cycle Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Gland Development Cellular Metabolic Process Negative Regulation Of BMP Signaling Pathway See more	RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Splicing Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Phase Transition Spliceosomal SnRNP Assembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MRNA Splice Site Selection Cellular Metabolic Process Ribonucleoprotein Complex Biogenesis Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Generation Of Catalytic Spliceosome For First Transesterification Step Regulation Of ERBB Signaling Pathway Regulation Of MRNA Processing Signal Transduction In Response To DNA Damage Regulation Of RNA Splicing Synaptic Growth At Neuromuscular Junction Regulation Of Cell Cycle Process Collateral Sprouting In Absence Of Injury Protein Ubiquitination Notch Signaling Pathway MRNA 5'-splice Site Recognition DNA Repair Protein Modification By Small Protein Conjugation DNA Damage Checkpoint Cellular Macromolecular Complex Assembly Collateral Sprouting Axon Midline Choice Point Recognition MRNA 3'-splice Site Recognition Protein Polyubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Gene Expression Axon Choice Point Recognition Negative Regulation Of Neuron Differentiation See more
Tagcloud ?		actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Difference) ?		actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Intersection) ?