SF3A1 and RBFOX2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		SF3A1	RBFOX2
Gene Name		splicing factor 3a, subunit 1, 120kDa	RNA binding protein, fox-1 homolog (C. elegans) 2
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding Poly(A) RNA Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 UBC WBP4 WDR77	50 interactors: APH1A ATN1 ATXN1 ATXN1L BOLL BRD7 C1orf94 CAMK2B CHAF1A DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH2 HNRNPK KHDRBS1 MAGED1 MAPK1IP1L MED7 NAF1 NR2E3 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBM22 RBM23 RBM42 RBPMS RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC TOLLIP U2AF2 VAC14 ZNF137P
Entrez ID		10291	23543
HPRD ID		06903	15231
Ensembl ID		ENSG00000099995	ENSG00000100320
Uniprot IDs		E9PAW1 Q15459	O43251
PDB IDs		1ZKH 2DT6 2DT7	2CQ3
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing RNA Metabolic Process MRNA Metabolic Process MRNA 3'-splice Site Recognition Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splice Site Selection Cellular Macromolecular Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Spliceosomal Complex Assembly Negative Regulation Of Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cell Cycle Arrest Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Cell Cycle Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Gland Development Cellular Metabolic Process Negative Regulation Of BMP Signaling Pathway	Gene Expression RNA Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of MRNA Processing Positive Regulation Of Cellular Protein Metabolic Process Metabolic Process DNA-templated Transcription, Initiation
Tagcloud ?		actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2	aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational
Tagcloud (Difference) ?		actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2	aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational
Tagcloud (Intersection) ?