SF3A1 and SF3A2

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)
HPRD (in vitro)

		SF3A1	SF3A2
Gene Name		splicing factor 3a, subunit 1, 120kDa	splicing factor 3a, subunit 2, 66kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex Catalytic Step 2 Spliceosome	Nucleoplasm Spliceosomal Complex Small Nuclear Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding	Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression	MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: APBB1 CSNK2A1 DDX42 GAS7 IL7R PRPF40A RBFOX2 RBM10 SF1 SF3A2 SF3A3 SMAD3 SMURF1 SP1 TCERG1 UBC WBP4 WDR77	8 interactors: APBB1 HTATSF1 PRPF40A RETN SF3A1 SMURF2 TCERG1 WBP4
Entrez ID		10291	8175
HPRD ID		06903	02877
Ensembl ID		ENSG00000099995	ENSG00000104897
Uniprot IDs		E9PAW1 Q15459	Q05DF2 Q15428
PDB IDs		1ZKH 2DT6 2DT7
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing RNA Metabolic Process MRNA Metabolic Process MRNA 3'-splice Site Recognition Gene Expression Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Nitrogen Compound Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splice Site Selection Cellular Macromolecular Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Ribonucleoprotein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Spliceosomal Complex Assembly Negative Regulation Of Cell Cycle DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Cycle Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Process Regulation Of RNA Metabolic Process Ribonucleoprotein Complex Biogenesis Cell Cycle Arrest Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Cell Cycle Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Gland Development Cellular Metabolic Process Negative Regulation Of BMP Signaling Pathway	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Splicing Nitrogen Compound Metabolic Process MRNA Processing Negative Regulation Of Thymidylate Synthase Biosynthetic Process MRNA Metabolic Process RNA Processing Positive Regulation Of Progesterone Secretion Regulation Of Progesterone Secretion MRNA 3'-splice Site Recognition Regulation Of Transcription From RNA Polymerase II Promoter Ubiquitin-dependent SMAD Protein Catabolic Process Negative Regulation Of Feeding Behavior MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Female Gonad Development Transcription, DNA-templated Regulation Of Feeding Behavior RNA Biosynthetic Process MRNA Cis Splicing, Via Spliceosome
Tagcloud ?		actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Difference) ?		actb aging analysed comprehensive cows deltact differed dominant durations eif2b2 follicle follicles follicular fsh gapdh genorm geometric granulosa maternal normfinder preovulatory programs ranking reference reffinder rnf20 suitable threshold ube2d2
Tagcloud (Intersection) ?