WWC2

Description		WW and C2 domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Protein Binding Kinase Binding Signaling Adaptor Activity Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Population Proliferation Cell Migration Hippo Signaling Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Heel bone mineral density ( 30598549) Height ( 20881960 28552196) Initial alcohol sensitivity ( 30276832)
Interacting Genes		5 interacting genes: CRYAA REPS1 WWC1 WWC3 YWHAQ
Entrez ID		80014
HPRD ID		12529
Ensembl ID		ENSG00000151718
Uniprot IDs		Q6AWC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Hippo Signaling Negative Regulation Of Hippo Signaling Negative Regulation Of Organ Growth Regulation Of Hippo Signaling Signaling Adaptor Activity Kinase Binding Regulation Of Organ Growth Negative Regulation Of Developmental Growth Regulation Of Growth Negative Regulation Of Macromolecule Biosynthetic Process Molecular Adaptor Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Growth Lens Fiber Cell Morphogenesis Negative Regulation Of Macromolecule Metabolic Process Tubulin Complex Assembly Negative Regulation Of Metabolic Process Cytosol Response To UV-A Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Developmental Growth Lens Morphogenesis In Camera-type Eye Embryonic Camera-type Eye Morphogenesis Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transport Structural Constituent Of Eye Lens Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Hippo Signaling Apoptotic Process Involved In Morphogenesis
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