PPFIBP2

Description		PPFIB scaffold protein 2
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GO Annotations	Cellular Component	Extracellular Space Cytosol Presynaptic Active Zone Presynapse
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Neuromuscular Junction Development
Pathways		Receptor-type tyrosine-protein phosphatases
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Cutaneous melanoma or hair colour ( 32341527) Fasting glucose ( 34059833) Hair color ( 29662168) Malaria ( 31844061) Prostate cancer ( 26443449 29892016) Prostate cancer (advanced) ( 29892016)
Interacting Genes		12 interacting genes: APP CLK1 CRK CRKL DTNB HSF4 PPFIA1 PPFIA2 PPFIA3 PRNP PTPRC TSG101
Entrez ID		8495
HPRD ID		04391
Ensembl ID		ENSG00000166387
Uniprot IDs		A0A804HJY3 A0A804HKA2 Q8ND30
PDB IDs		3QH9
Enriched GO Terms of Interacting Partners?		Helper T Cell Diapedesis Postsynaptic Specialization Organization Cerebellar Neuron Development Dendrite Development Regulation Of T Cell Migration Regulation Of Protein Localization To Membrane Presynaptic Active Zone Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Protein Localization Diapedesis Regulation Of Lymphocyte Migration Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Regulation Of Protein Localization Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Synapse Synapse Organization Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Membrane Positive Regulation Of Receptor Clustering Reelin-mediated Signaling Pathway Postsynaptic Specialization Assembly Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Regulation Of Calcium-mediated Signaling Response To Yeast Regulation Of Cellular Component Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Intracellular Copper Ion Homeostasis Regulation Of Cell Projection Organization Regulation Of Receptor Clustering Heparan Sulfate Proteoglycan Binding Positive Regulation Of Rac Protein Signal Transduction Copper Ion Homeostasis Cellular Response To Copper Ion Regulation Of Postsynapse Organization Regulation Of Mononuclear Cell Migration Molecular Function Activator Activity Negative Regulation Of Interleukin-2 Production Ephrin Receptor Binding Positive Regulation Of Endocytosis Positive Regulation Of MAPK Cascade Cell Junction Organization Dendrite Regulation Of Rac Protein Signal Transduction Response To Copper Ion Positive Regulation Of ERK1 And ERK2 Cascade T Cell Migration Modulation Of Chemical Synaptic Transmission Regulation Of Immune Response Negative Regulation Of Transcription By RNA Polymerase II
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