CEP19 and EVI5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEP19	EVI5
Description		centrosomal protein 19	ecotropic viral integration site 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection	Nucleus Cytoplasm Centrosome Spindle Cytosol Cytoskeleton
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Cell Projection Organization Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31959851)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein B levels ( 32203549) Asthma or allergic disease (pleiotropy) ( 29785011) Body fat percentage and LDL-C (pairwise) ( 33619380) Cholesterol, total ( 25961943 24097068 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 25961943 30275531) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 33339817 32154731) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 19525955 31604244 21833088 24076602 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 30275531 28334899 33339817)
Interacting Genes		47 interacting genes: AK4 ANAPC15 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PGCKA1 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81	21 interacting genes: ARL4A AURKB BIRC5 CCDC185 CEP19 CSNK1D ELOA FAM161A FBXO5 IMP3 INCENP LENG1 LMO1 MB21D2 MCRS1 MORF4L2 PRPF31 STX3 TCEANC TNFAIP8L1 ZNF446
Entrez ID		84984	7813
HPRD ID		17488	04249
Ensembl ID		ENSG00000174007	ENSG00000067208
Uniprot IDs		A8MX07 Q96LK0	A0A804HIC4 A0A9L9PXE3 A0A9L9PXL1 A0A9L9PYE8 O60447 Q59FE7
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Chromosome Passenger Complex Spindle Assembly Spindle Microtubule Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Sister Chromatid Separation Spindle Organization Positive Regulation Of Cell Cycle Checkpoint Regulation Of Chromosome Separation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Nucleoplasm Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Chromosome Segregation Regulation Of Sister Chromatid Segregation Spindle Positive Regulation Of Chromosome Separation Regulation Of Chromosome Organization Microtubule Cytoskeleton Organization Regulation Of Mitotic Nuclear Division Organelle Assembly Membraneless Organelle Assembly Regulation Of Chromosome Segregation Positive Regulation Of Cytokinesis Mitotic Spindle Assembly Regulation Of Nuclear Division Chromosome, Centromeric Region Kinetochore Mitotic Cytokinesis Chromocenter Negative Regulation Of Chromosome Organization Regulation Of Cytokinesis Positive Regulation Of Cell Division Mitotic Spindle Organization Cytoskeleton-dependent Cytokinesis Cytoskeleton Positive Regulation Of Cell Cycle Process Microtubule-based Process Spindle Midzone Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Cell Cycle Mitotic Cell Cycle
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