CEP19 and PRAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEP19	PRAP1
Description		centrosomal protein 19	proline rich acidic protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection	Extracellular Region Endoplasmic Reticulum
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Triglyceride Binding
	Biological Process	Cell Projection Organization Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	DNA Damage Response DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Apoptotic Process Cellular Response To X-ray Deactivation Of Mitotic Spindle Assembly Checkpoint Positive Regulation Of Intestinal Lipid Absorption Positive Regulation Of Triglyceride Transport Positive Regulation Of Phospholipid Transport
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31959851)	Nonunion in individuals with fractures ( 30680360)
Interacting Genes		47 interacting genes: AK4 ANAPC15 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PGCKA1 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81	11 interacting genes: AHNAK2 ASPH CEP19 GRB2 HSPA6 MEOX2 MRFAP1 SGTA SGTB UBQLN1 UBQLN2
Entrez ID		84984	118471
HPRD ID		17488	17898
Ensembl ID		ENSG00000174007	ENSG00000165828
Uniprot IDs		A8MX07 Q96LK0	A6XND8 Q96NZ9
PDB IDs
Enriched GO Terms of Interacting Partners?			TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Targeting To ER COP9 Signalosome Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Guanyl-nucleotide Exchange Factor Adaptor Activity Negative Regulation Of Store-operated Calcium Channel Activity Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment Cytoplasm Protein Targeting To Membrane Positive Regulation Of Protein Metabolic Process Peptidyl-aspartic Acid 3-dioxygenase Activity Regulation Of Transmembrane Transporter Activity Roof Of Mouth Development Regulation Of Monoatomic Ion Transmembrane Transporter Activity Grb2-EGFR Complex Autophagosome Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Protein Catabolic Process Autophagosome Assembly Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Cellular Response To Stress Autophagosome Organization Negative Regulation Of Toll-like Receptor 3 Signaling Pathway BAT3 Complex Binding Negative Regulation Of Clathrin-dependent Endocytosis Vesicle Targeting, To, From Or Within Golgi Activation Of Store-operated Calcium Channel Activity Identical Protein Binding Somite Specification Proteasomal Protein Catabolic Process Positive Regulation Of Store-operated Calcium Channel Activity Regulation Of Calcium Ion Transmembrane Transport Neurotrophin TRKA Receptor Binding Cellular Heat Acclimation Regulation Of Cellular Response To Stress Negative Regulation Of ERAD Pathway
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