CEP19 and ROBO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CEP19	ROBO4
Description		centrosomal protein 19	roundabout guidance receptor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Cilium Ciliary Basal Body Cell Projection	Plasma Membrane External Side Of Plasma Membrane Membrane Axon Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Signaling Receptor Activity Cell-cell Adhesion Mediator Activity
	Biological Process	Cell Projection Organization Microtubule Anchoring At Centrosome Cilium Assembly Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Cell Differentiation Regulation Of Cell Migration Blood Vessel Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Establishment Of Endothelial Barrier Dendrite Self-avoidance
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31959851)	Breast cancer (survival) ( 25890600) Venous thromboembolism ( 32232851)
Interacting Genes		47 interacting genes: AK4 ANAPC15 CALCOCO1 CCDC102B CCDC106 CCDC74A CDR1 CREB3L2 CREB3L3 EVI5 FOXR1 GMEB2 GNL3 HSPB2 HSPB2-C11orf52 KIAA1958 KXD1 LYSMD2 NOTO PAPSS2 PEX13 PGCKA1 PIBF1 PICK1 PIK3R3 PLEKHO1 PRAP1 PRKAR1B PTPN23 RABL2B REL ROBO4 SENP3 SYNE4 TNNI1 TRAIP TSPYL2 TVP23B TXLNB VCP VPS52 ZBTB10 ZBTB14 ZFP1 ZNF420 ZNF438 ZNF81	5 interacting genes: CEP19 ENAH PPARG RXRA THRB
Entrez ID		84984	54538
HPRD ID		17488	09604
Ensembl ID		ENSG00000174007	ENSG00000154133
Uniprot IDs		A8MX07 Q96LK0	B4DYV8 Q8WZ75
PDB IDs
Enriched GO Terms of Interacting Partners?			Retinoic Acid Receptor Signaling Pathway Nuclear Receptor Activity MRNA Transcription By RNA Polymerase II Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway MRNA Transcription DNA Binding Domain Binding Positive Regulation Of Lipoprotein Transport Regulation Of Thyroid Hormone Receptor Signaling Pathway LBD Domain Binding Nuclear Receptor-mediated Signaling Pathway Peroxisome Proliferator Activated Receptor Signaling Pathway RNA Polymerase II Transcription Regulator Complex Hormone-mediated Signaling Pathway Monocyte Differentiation WW Domain Binding Intracellular Receptor Signaling Pathway Positive Regulation Of Cholesterol Efflux Peptide Binding Cellular Response To Low-density Lipoprotein Particle Stimulus Positive Regulation Of Cholesterol Transport Cellular Response To Lipoprotein Particle Stimulus Transcription By RNA Polymerase II Transcription Coregulator Binding Regulation Of Cholesterol Efflux Enzyme Binding Regulation Of Cholesterol Transport DNA-templated Transcription Sequence-specific DNA Binding Positive Regulation Of Lipid Transport Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment MRNA Metabolic Process DNA-binding Transcription Factor Activity Negative Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Double-stranded DNA Binding Positive Regulation Of Adiponectin Secretion Retinal Cone Cell Apoptotic Process Female Courtship Behavior Regulation Of Lipid Transport Positive Regulation Of Lipid Metabolic Process Myeloid Leukocyte Differentiation Cell Maturation Vitamin D Response Element Binding Thyroid Hormone Receptor Signaling Pathway Prostaglandin Receptor Activity Negative Regulation Of Female Receptivity Vesicle Targeting, To, From Or Within Golgi Nucleobase-containing Compound Biosynthetic Process Receptor Complex Developmental Maturation Negative Regulation Of Mitochondrial Fission
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