AOPEP and BUB1

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		AOPEP	BUB1
Description		aminopeptidase O (putative)	BUB1 mitotic checkpoint serine/threonine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Chromosome, Centromeric Region Kinetochore Outer Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Membrane
	Molecular Function	Aminopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metalloaminopeptidase Activity	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity Histone H2A Kinase Activity
	Biological Process	Proteolysis	Chromatin Remodeling Apoptotic Process Chromosome Segregation Regulation Of Sister Chromatid Cohesion Mitotic Spindle Assembly Checkpoint Signaling Intracellular Signal Transduction Cell Division Meiotic Sister Chromatid Cohesion, Centromeric Regulation Of Chromosome Segregation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)
Interacting Genes		9 interacting genes: BMPR1A BUB1 CDH1 CDKN2A DLC1 EGFR MLH3 NRAS SMAD4	64 interacting genes: AKT1 ALDOB ANP32B AOPEP AP1B1 AP2B1 AP3B1 AP4B1 APC ARIH2 BAAT BUB3 CCDC180 CDC14B CDC20 CDK1 CDK8 CORO2A CRK CTSV CYLC2 DVL1 EIF4EBP1 FANCC FBP1 FBP2 FBXO7 FRAT2 GALNT12 HDAC1 HEMGN HRAS HSD17B3 IGFBP3 KNL1 LEF1 MAP2K1 MAPK3 MSANTD3 NANS PLK1 PPP2CB PPP3R2 RAE1 RASA1 RDH12 SEC61B SFRP2 SFRP4 SHC1 SMAD1 STX17 SVIL TBC1D2 TDRD7 TGFB1 TMEFF1 TMOD1 TRMO TSTD2 UBC XPA ZNF189 ZNF510
Entrez ID		84909	699
HPRD ID		07476	03907
Ensembl ID		ENSG00000148120	ENSG00000169679
Uniprot IDs		Q8N6M6	B4DYG2 O43683
PDB IDs			2LAH 4A1G 4QPM 4R8Q 5DMZ 6F7B 7B1F 7B1H 7B1J
Enriched GO Terms of Interacting Partners?		Regulation Of Growth Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Mesendoderm Development Regulation Of Transforming Growth Factor Beta2 Production Regulation Of MiRNA Metabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Cardiocyte Differentiation Cardiac Conduction System Development Regulation Of Epithelial Cell Proliferation Regulation Of Cell Growth Regulation Of Cellular Component Organization Epithelial Cell Proliferation Outflow Tract Septum Morphogenesis Regulation Of Cell Population Proliferation Negative Regulation Of Developmental Process Cellular Response To BMP Stimulus Pituitary Gland Development Negative Regulation Of Cell Growth Animal Organ Morphogenesis Endoderm Development Positive Regulation Of Epithelial Cell Proliferation Intracellular Signal Transduction Negative Regulation Of Cell-matrix Adhesion Ventricular Septum Morphogenesis Negative Regulation Of Growth Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Multicellular Organismal Process MAPK Cascade Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Neural Crest Cell Differentiation Embryonic Digit Morphogenesis Gland Development SMAD Binding Cellular Response To Growth Factor Stimulus Tube Morphogenesis Neural Plate Mediolateral Regionalization Paraxial Mesoderm Structural Organization Regulation Of Cardiac Muscle Cell Apoptotic Process Heart Morphogenesis Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Cell Development Cell Population Proliferation Tissue Development Fibrous Ring Of Heart Morphogenesis Mesoderm Development Positive Regulation Of Cardiac Ventricle Development Negative Regulation Of Cellular Component Organization Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Clathrin Adaptor Complex Regulation Of Organelle Organization Regulation Of Cellular Component Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Regulation Of Cell Cycle Membrane Coat Cytosol Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Fructose 1,6-bisphosphate Metabolic Process Regulation Of Sister Chromatid Segregation Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Cytoskeleton Organization Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Separation Regulation Of Chromosome Segregation Insulin Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Protein Localization To Kinetochore Positive Regulation Of Ubiquitin-protein Transferase Activity Phosphoric Ester Hydrolase Activity Fructose 1,6-bisphosphate 1-phosphatase Activity Golgi Inheritance Negative Regulation Of Mitotic Nuclear Division Intracellular Signal Transduction Fructose Metabolic Process Negative Regulation Of Cell Cycle Phase Transition Regulation Of Cellular Localization Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Localization Regulation Of Plasma Membrane Bounded Cell Projection Organization Phosphotyrosine Residue Binding Regulation Of Cell Projection Organization Regulation Of Chromosome Organization Positive Regulation Of Protein Localization Protein Kinase Binding Regulation Of Protein Localization To Membrane Gluconeogenesis Schwann Cell Development Negative Regulation Of Cell Cycle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?