AOPEP

Description		aminopeptidase O (putative)
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm
	Molecular Function	Aminopeptidase Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Proteolysis
Pathways
Drugs
Diseases
GWAS		Hodgkin's lymphoma ( 34216518)
Novel Interacting Genes		1 novel interacting genes: PACS1
Interacting Genes		9 interacting genes: BMPR1A BUB1 CDH1 CDKN2A DLC1 EGFR MLH3 NRAS SMAD4
Entrez ID		84909
HPRD ID		07476
Ensembl ID		ENSG00000148120
Uniprot IDs		Q8N6M6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Growth Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Mesendoderm Development Regulation Of Transforming Growth Factor Beta2 Production Regulation Of MiRNA Metabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Cardiocyte Differentiation Cardiac Conduction System Development Regulation Of Epithelial Cell Proliferation Regulation Of Cell Growth Regulation Of Cellular Component Organization Epithelial Cell Proliferation Outflow Tract Septum Morphogenesis Regulation Of Cell Population Proliferation Negative Regulation Of Developmental Process Cellular Response To BMP Stimulus Pituitary Gland Development Negative Regulation Of Cell Growth Animal Organ Morphogenesis Endoderm Development Positive Regulation Of Epithelial Cell Proliferation Intracellular Signal Transduction Negative Regulation Of Cell-matrix Adhesion Ventricular Septum Morphogenesis Negative Regulation Of Growth Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Multicellular Organismal Process MAPK Cascade Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Neural Crest Cell Differentiation Embryonic Digit Morphogenesis Gland Development SMAD Binding Cellular Response To Growth Factor Stimulus Tube Morphogenesis Neural Plate Mediolateral Regionalization Paraxial Mesoderm Structural Organization Regulation Of Cardiac Muscle Cell Apoptotic Process Heart Morphogenesis Cardiac Muscle Tissue Morphogenesis Negative Regulation Of Cell Development Cell Population Proliferation Tissue Development Fibrous Ring Of Heart Morphogenesis Mesoderm Development Positive Regulation Of Cardiac Ventricle Development Negative Regulation Of Cellular Component Organization Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric
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