GLIS2 and XAB2

Number of citations of the paper that reports this interaction (PMID 17289029)
9

Data Source:
BioGRID (two hybrid)

		GLIS2	XAB2
Gene Name		GLIS family zinc finger 2	XPA binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Nervous System Development Cell Differentiation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	MRNA Splicing, Via Spliceosome Blastocyst Development DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription, DNA-templated
Pathways			Nucleotide Excision Repair Transcription-coupled NER (TC-NER) Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in TC-NER
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CPSF1 CTNNB1 GPSM2 RBFOX2 SPECC1L TRIM32 U2AF2 WNK1 XAB2	11 interactors: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 POLR2A PPIE SMAD9 XPA
Entrez ID		84662	56949
HPRD ID		12256	18306
Ensembl ID		ENSG00000126603	ENSG00000076924
Uniprot IDs		Q9BZE0	Q9HCS7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Lung Cell Differentiation Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus Intracellular Steroid Hormone Receptor Signaling Pathway DNA-templated Transcription, Termination RNA Export From Nucleus Positive Regulation Of Type I Interferon Production MRNA 3'-end Processing Negative Regulation Of Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of Fibroblast Proliferation Regulation Of RNA Splicing RNA 3'-end Processing Regulation Of Type I Interferon Production Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nuclear Export MRNA Transport Negative Regulation Of Gene Expression Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion RNA Transport Regulation Of Microtubule Cytoskeleton Organization RNA Localization Positive Regulation Of Determination Of Dorsal Identity Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Generation Of Neurons Regulation Of Microtubule-based Process Central Nervous System Vasculogenesis Radial Glia Guided Migration Of Purkinje Cell Trachea Formation Regulation Of Definitive Erythrocyte Differentiation	Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Transcription-coupled Nucleotide-excision Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process RNA Metabolic Process RNA Splicing Gene Expression Response To UV MRNA Processing Regulation Of Viral Process MRNA Metabolic Process Response To X-ray RNA Processing DNA Repair Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Response To Light Stimulus Regulation Of Viral Genome Replication Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Transcription, RNA-templated Response To Radiation DNA Metabolic Process Response To Abiotic Stimulus Multicellular Organism Growth Cellular Metabolic Process Response To Ionizing Radiation Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Response To Toxic Substance Intrinsic Apoptotic Signaling Pathway Mullerian Duct Regression Cellular Response To Stress Activation Of JNKK Activity Pyrimidine Dimer Repair Transcription From RNA Polymerase II Promoter
Tagcloud ?		aire amp creb1 drive erg forkhead foxm1 foxp3 get grainyhead grhl1 hnf1a hnf4a hub hubs interconnected m1 pu quantitatively spi1 stimulatory tcf tp53l tp63 transactivator trop trop2 web wilms	aspect associates atra cockayne corepressor deacetylase defining dermatologic embryogenesis hl60 imr interfering lethality mol motifs neuroblastoma photoaging physiologic pigmentosum preimplantation preneoplastic promyelocytic raralpha retinoids rhabdomyosarcoma splicing tetratricopeptide xeroderma xpa
Tagcloud (Difference) ?		aire amp creb1 drive erg forkhead foxm1 foxp3 get grainyhead grhl1 hnf1a hnf4a hub hubs interconnected m1 pu quantitatively spi1 stimulatory tcf tp53l tp63 transactivator trop trop2 web wilms	aspect associates atra cockayne corepressor deacetylase defining dermatologic embryogenesis hl60 imr interfering lethality mol motifs neuroblastoma photoaging physiologic pigmentosum preimplantation preneoplastic promyelocytic raralpha retinoids rhabdomyosarcoma splicing tetratricopeptide xeroderma xpa
Tagcloud (Intersection) ?