GLIS2 and SPECC1L

Number of citations of the paper that reports this interaction (PMID 17289029)
9

Data Source:
BioGRID (two hybrid)

		GLIS2	SPECC1L
Gene Name		GLIS family zinc finger 2	sperm antigen with calponin homology and coiled-coil domains 1-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Cytoplasm Microtubule Organizing Center Spindle Gap Junction Filamentous Actin
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Nervous System Development Cell Differentiation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Microtubule Depolymerization Cell Cycle Cell Migration Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Depolymerization Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CPSF1 CTNNB1 GPSM2 RBFOX2 SPECC1L TRIM32 U2AF2 WNK1 XAB2	5 interactors: APC GLIS2 KIAA0368 UBC UBE2I
Entrez ID		84662	23384
HPRD ID		12256	11080
Ensembl ID		ENSG00000126603	ENSG00000100014
Uniprot IDs		Q9BZE0	B2RMV2 Q69YQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Lung Cell Differentiation Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus Intracellular Steroid Hormone Receptor Signaling Pathway DNA-templated Transcription, Termination RNA Export From Nucleus Positive Regulation Of Type I Interferon Production MRNA 3'-end Processing Negative Regulation Of Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of Fibroblast Proliferation Regulation Of RNA Splicing RNA 3'-end Processing Regulation Of Type I Interferon Production Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nuclear Export MRNA Transport Negative Regulation Of Gene Expression Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion RNA Transport Regulation Of Microtubule Cytoskeleton Organization RNA Localization Positive Regulation Of Determination Of Dorsal Identity Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Generation Of Neurons Regulation Of Microtubule-based Process Central Nervous System Vasculogenesis Radial Glia Guided Migration Of Purkinje Cell Trachea Formation Regulation Of Definitive Erythrocyte Differentiation	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Proteolysis Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Catabolic Process Positive Regulation Of SUMO Transferase Activity Mitotic Cell Cycle Process Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Positive Regulation Of Wnt Signaling Pathway Mitotic Cell Cycle Checkpoint Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Odontogenesis Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Metaphase/anaphase Transition Of Mitotic Cell Cycle Positive Regulation Of Signal Transduction Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Regulation Of Wnt Signaling Pathway Negative Regulation Of Transferase Activity Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle
Tagcloud ?		aire amp creb1 drive erg forkhead foxm1 foxp3 get grainyhead grhl1 hnf1a hnf4a hub hubs interconnected m1 pu quantitatively spi1 stimulatory tcf tp53l tp63 transactivator trop trop2 web wilms
Tagcloud (Difference) ?		aire amp creb1 drive erg forkhead foxm1 foxp3 get grainyhead grhl1 hnf1a hnf4a hub hubs interconnected m1 pu quantitatively spi1 stimulatory tcf tp53l tp63 transactivator trop trop2 web wilms
Tagcloud (Intersection) ?