XAB2 and ILF3

Number of citations: 0 (PubMedID 22365833)
Data Source: BioGRID (two hybrid)

		XAB2	ILF3
Name		XPA binding protein 2	interleukin enhancer binding factor 3
Structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol Membrane Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Virus Receptor Activity DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Blastocyst Development DNA Repair Transcription-coupled Nucleotide-excision Repair DNA-templated Transcription RNA Processing MRNA Processing DNA Damage Response RNA Splicing Cerebral Cortex Development	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Symbiont Entry Into Host Cell Defense Response To Virus Spliceosome-depend Formation Of Circular RNA
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	Regulation of CDH11 gene transcription Regulation of CDH11 gene transcription PKR-mediated signaling
GWAS		No GWAS studies recorded	Bipolar disorder ( 31043756 ) Chronotype ( 30696823 ) Height ( 25282103 25429064 ) Obesity-related traits ( 23251661 ) Psoriasis ( 23143594 25574825 25903422 ) Psoriasis vulgaris ( 26626624 ) Rheumatoid arthritis ( 30423114 ) Systemic lupus erythematosus ( 28714469 )
Interacting Genes		18 interacting genes: CACHD1 DHX16 DSCR9 ERCC6 ERCC8 GLIS2 ILF3 MIR106B MIR34B MIRLET7E MIRLET7G MIRLET7I POLR2A PPIE RNF10 SMAD9 SUMO2 XPA	44 interacting genes: CEBPA DHX9 DUX4 EIF2AK2 EP300 ERBB2 ERG ESR1 FUS GDF9 HNRNPH2 IL7R IRF3 IRF9 KRTAP4-12 LINC00624 LNX1 MAGEA11 MAPK1 MDFI NDRG1 OGT PLSCR1 PRMT1 PRMT5 PSMA3 PTEN RBM5 RBPMS SF1 SF3B4 SMN1 SPOP TRIM55 TRIM63 TRIP6 UBC USP7 VPS37C XAB2 XPO5 YWHAH ZNF346 ZNF830
Entrez ID		56949	3609
HPRD ID		18306	04420
Ensembl ID		ENSG00000076924	ENSG00000129351
Uniprot IDs		Q9HCS7	Q12906
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7ABI 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD	2L33 3P1X 7RJM 7RJQ
GO Terms Enriched among Interactors		MRNA Base-pairing Post-transcriptional Repressor Activity MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulatory NcRNA-mediated Gene Silencing RISC Complex Positive Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Nucleotide-excision Repair Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Regulation Of Metabolic Process Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Transcription-coupled Nucleotide-excision Repair MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process MRNA 3'-UTR Binding Response To X-ray Positive Regulation Of MRNA Metabolic Process Response To UV Base-excision Repair Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Gene Expression Regulation Of Transcription-coupled Nucleotide-excision Repair Site Of DNA Damage Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Translation Nucleotide-excision Repair, DNA Damage Recognition Regulation Of MRNA Stability MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription By RNA Polymerase II RNA Splicing, Via Transesterification Reactions Regulation Of RNA Stability MiRNA-mediated Gene Silencing By Inhibition Of Translation DNA-templated Transcription Elongation Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein	Nucleoplasm Nucleus Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding RNA Splicing Rhythmic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein-RNA Complex Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Gene Expression Cytosol Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Cytoplasm Positive Regulation Of RNA Metabolic Process RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex Assembly Protein Modification Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleic Acid Binding Regulation Of Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions DNA-templated Transcription Termination RNA Binding Nucleic Acid Metabolic Process TORC1 Signaling Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Response To Stress Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cell Population Proliferation Macromolecule Biosynthetic Process Cellular Component Assembly RNA Processing Cellular Response To Nutrient Levels Protein-containing Complex Assembly RISC Complex Binding Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation TOR Signaling Chromatin DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process