XAB2 and ERCC8

Number of citations of the paper that reports this interaction (PMID 10944529)
25

Data Source:
HPRD (in vivo, in vitro)

		XAB2	ERCC8
Gene Name		XPA binding protein 2	excision repair cross-complementation group 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Catalytic Step 2 Spliceosome	Nucleotide-excision Repair Complex Nucleus Nucleoplasm Nuclear Matrix Cul4A-RING E3 Ubiquitin Ligase Complex Protein Complex
	Molecular Function	Protein Binding	DNA Helicase Activity Ubiquitin-protein Transferase Activity Protein Binding DNA-dependent ATPase Activity Protein Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome Blastocyst Development DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription, DNA-templated	Protein Polyubiquitination DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Cellular Response To DNA Damage Stimulus Response To Oxidative Stress Response To UV Response To X-ray Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Repair Protein Autoubiquitination
Pathways		Nucleotide Excision Repair Transcription-coupled NER (TC-NER) Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in TC-NER	Nucleotide Excision Repair Transcription-coupled NER (TC-NER) Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in TC-NER
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 POLR2A PPIE SMAD9 XPA	8 interactors: CBR1 CSNK2B DDB1 ERCC6 GTF2H2 TOP1 UQCRQ XAB2
Entrez ID		56949	1161
HPRD ID		18306	07523
Ensembl ID		ENSG00000076924	ENSG00000049167
Uniprot IDs		Q9HCS7	B4DGZ9 Q13216
PDB IDs			4A11
Enriched GO Terms of Interacting Partners?		Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Transcription-coupled Nucleotide-excision Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process RNA Metabolic Process RNA Splicing Gene Expression Response To UV MRNA Processing Regulation Of Viral Process MRNA Metabolic Process Response To X-ray RNA Processing DNA Repair Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Response To DNA Damage Stimulus Response To Light Stimulus Regulation Of Viral Genome Replication Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Transcription, RNA-templated Response To Radiation DNA Metabolic Process Response To Abiotic Stimulus Multicellular Organism Growth Cellular Metabolic Process Response To Ionizing Radiation Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Response To Toxic Substance Intrinsic Apoptotic Signaling Pathway Mullerian Duct Regression Cellular Response To Stress Activation Of JNKK Activity Pyrimidine Dimer Repair Transcription From RNA Polymerase II Promoter	Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair DNA Metabolic Process Response To UV Nucleotide-excision Repair, DNA Damage Removal DNA Repair Transcription Elongation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter Cellular Response To DNA Damage Stimulus Response To Light Stimulus Positive Regulation Of Viral Process DNA-templated Transcription, Elongation Response To Radiation Viral Process Subthalamus Development Cellular Response To Stress DNA Catabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Regulation Of Viral Process Cellular Metabolic Process Phosphorylation UV-damage Excision Repair Vitamin K Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Viral Release From Host Cell Adiponectin-activated Signaling Pathway Activation Of JNKK Activity Wnt Signaling Pathway Endothelial Tube Morphogenesis Pyramidal Neuron Development Pons Development Histone H2A Monoubiquitination Pyramidal Neuron Differentiation Embryonic Cleavage Pyrimidine Dimer Repair G-protein Coupled Receptor Internalization Response To Abiotic Stimulus Thalamus Development Histone H2A Ubiquitination Response To UV-B Cyclooxygenase Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Blood Vessel Endothelial Cell Migration Histone Monoubiquitination Positive Regulation Of Viral Genome Replication Regulation Of Activin Receptor Signaling Pathway Prostaglandin Biosynthetic Process Regulation Of Viral Release From Host Cell MRNA Processing Hypothalamus Development
Tagcloud ?		aspect associates atra cockayne corepressor deacetylase defining dermatologic embryogenesis hl60 imr interfering lethality mol motifs neuroblastoma photoaging physiologic pigmentosum preimplantation preneoplastic promyelocytic raralpha retinoids rhabdomyosarcoma splicing tetratricopeptide xeroderma xpa
Tagcloud (Difference) ?		aspect associates atra cockayne corepressor deacetylase defining dermatologic embryogenesis hl60 imr interfering lethality mol motifs neuroblastoma photoaging physiologic pigmentosum preimplantation preneoplastic promyelocytic raralpha retinoids rhabdomyosarcoma splicing tetratricopeptide xeroderma xpa
Tagcloud (Intersection) ?