GLIS2 and CPSF1

Number of citations of the paper that reports this interaction (PMID 17289029)
9

Data Source:
BioGRID (two hybrid)

		GLIS2	CPSF1
Gene Name		GLIS family zinc finger 2	cleavage and polyadenylation specific factor 1, 160kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	MRNA 3'-UTR Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Nervous System Development Cell Differentiation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Transport of Mature mRNA Derived from an Intronless Transcript RNA Polymerase II Transcription Transport of Mature mRNAs Derived from Intronless Transcripts Cleavage of Growing Transcript in the Termination Region mRNA Splicing - Major Pathway mRNA 3'-end processing Processing of Intronless Pre-mRNAs Processing of Capped Intronless Pre-mRNA Transport of Mature Transcript to Cytoplasm RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CPSF1 CTNNB1 GPSM2 RBFOX2 SPECC1L TRIM32 U2AF2 WNK1 XAB2	18 interactors: CSTF2T CSTF3 CTD GLIS2 HMOX1 IL7R MCM2 NEDD4 PAPOLA POLR2A PRRC2A REL RRAGA TAF11 TAF12 TAF13 TAF5 TAF7
Entrez ID		84662	29894
HPRD ID		12256	05823
Ensembl ID		ENSG00000126603	ENSG00000071894
Uniprot IDs		Q9BZE0	Q10570
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription Lung Cell Differentiation Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus Intracellular Steroid Hormone Receptor Signaling Pathway DNA-templated Transcription, Termination RNA Export From Nucleus Positive Regulation Of Type I Interferon Production MRNA 3'-end Processing Negative Regulation Of Cellular Metabolic Process Regulation Of MRNA Processing Regulation Of Fibroblast Proliferation Regulation Of RNA Splicing RNA 3'-end Processing Regulation Of Type I Interferon Production Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Nuclear Export MRNA Transport Negative Regulation Of Gene Expression Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion RNA Transport Regulation Of Microtubule Cytoskeleton Organization RNA Localization Positive Regulation Of Determination Of Dorsal Identity Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Generation Of Neurons Regulation Of Microtubule-based Process Central Nervous System Vasculogenesis Radial Glia Guided Migration Of Purkinje Cell Trachea Formation Regulation Of Definitive Erythrocyte Differentiation	Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process MRNA Processing RNA Polyadenylation Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Gene Expression Termination Of RNA Polymerase II Transcription MRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Viral Transcription RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Spermine Transport Transmission Of Virus Development Involved In Symbiotic Interaction Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Viral Transcription Response To Cytokine Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Viral Process
Tagcloud ?		aire amp creb1 drive erg forkhead foxm1 foxp3 get grainyhead grhl1 hnf1a hnf4a hub hubs interconnected m1 pu quantitatively spi1 stimulatory tcf tp53l tp63 transactivator trop trop2 web wilms
Tagcloud (Difference) ?		aire amp creb1 drive erg forkhead foxm1 foxp3 get grainyhead grhl1 hnf1a hnf4a hub hubs interconnected m1 pu quantitatively spi1 stimulatory tcf tp53l tp63 transactivator trop trop2 web wilms
Tagcloud (Intersection) ?