ST6GAL2 and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ST6GAL2	PGRMC2
Description		ST6 beta-galactoside alpha-2,6-sialyltransferase 2	progesterone receptor membrane component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane	Extracellular Region Nucleus Nuclear Envelope Nucleoplasm Endoplasmic Reticulum Endomembrane System Membrane Synapse Glutamatergic Synapse
	Molecular Function	Beta-galactoside Alpha-2,6-sialyltransferase Activity Protein Binding Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity	Nuclear Steroid Receptor Activity Steroid Binding Protein Binding Lipid Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Oligosaccharide Metabolic Process Sialylation	Heme Transport Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Adipose Tissue Development
Pathways		Sialic acid metabolism	RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Heme signaling
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Serum immune biomarker levels ( 32066700)	Bone mineral density (total hip) ( 29883787)
Interacting Genes		16 interacting genes: AQP6 CD53 CREB3 FNDC9 GIPC3 GOLM1 GPX8 HSD17B13 PGRMC2 PSCA SLC26A1 SLC39A2 SLC7A1 TIMMDC1 TMEM14B TMEM237	55 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LINC00632 LPAR3 MALL MFHAS1 ORMDL1 PEDS1-UBE2V1 PEX16 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		84620	10424
HPRD ID		12237	09665
Ensembl ID		ENSG00000144057	ENSG00000164040
Uniprot IDs		Q96JF0	O15173
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Myelination Axon Ensheathment Alkenylglycerophosphocholine Hydrolase Activity Compact Myelin
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