ST6GAL2 and GIPC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ST6GAL2	GIPC3
Description		ST6 beta-galactoside alpha-2,6-sialyltransferase 2	GIPC PDZ domain containing family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Golgi Cisterna Membrane
	Molecular Function	Beta-galactoside Alpha-2,6-sialyltransferase Activity Protein Binding Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Protein Glycosylation Oligosaccharide Metabolic Process Sialylation
Pathways		Sialic acid metabolism
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Serum immune biomarker levels ( 32066700)
Interacting Genes		16 interacting genes: AQP6 CD53 CREB3 FNDC9 GIPC3 GOLM1 GPX8 HSD17B13 PGRMC2 PSCA SLC26A1 SLC39A2 SLC7A1 TIMMDC1 TMEM14B TMEM237	3 interacting genes: FZD3 PLEKHA2 ST6GAL2
Entrez ID		84620	126326
HPRD ID		12237	16386
Ensembl ID		ENSG00000144057	ENSG00000179855
Uniprot IDs		Q96JF0	A0A2R8Y651 Q8TF64
PDB IDs
Enriched GO Terms of Interacting Partners?			PDZ Domain Binding Serotonergic Neuron Axon Guidance Dopaminergic Neuron Axon Guidance Negative Regulation Of Mitotic Cell Cycle, Embryonic Midbrain Morphogenesis Beta-galactoside Alpha-2,6-sialyltransferase Activity Regulation Of Mitotic Cell Cycle, Embryonic Cell Proliferation In Midbrain Negative Regulation Of Execution Phase Of Apoptosis Sympathetic Ganglion Development Sialylation Filopodium Tip Wnt Receptor Activity Ganglion Development Commissural Neuron Axon Guidance Motor Neuron Migration Sialyltransferase Activity Post-anal Tail Morphogenesis Establishment Of Planar Polarity Laminin Binding Positive Regulation Of Neuroblast Proliferation Presynaptic Active Zone Membrane Wnt-protein Binding Phosphatidylinositol-3,4-bisphosphate Binding Fibronectin Binding Midbrain Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Response To Electrical Stimulus Presynaptic Active Zone Hair Follicle Development Regulation Of Neuroblast Proliferation Non-canonical Wnt Signaling Pathway Positive Regulation Of Neural Precursor Cell Proliferation Oligosaccharide Metabolic Process Inner Ear Morphogenesis Positive Regulation Of Cell-matrix Adhesion Lateral Plasma Membrane Golgi Cisterna Membrane Hair Cycle Process
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