KLF11 and CBX1

Number of citations of the paper that reports this interaction (PMID 22318730)
13

Data Source:
BioGRID (pull down)

		KLF11	CBX1
Gene Name		Kruppel-like factor 11	chromobox homolog 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Chromosome, Centromeric Region Chromatin Female Pronucleus Male Pronucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Metal Ion Binding	Chromatin Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Histone Methyltransferase Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Apoptotic Process Cellular Response To Peptide	Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Body mass index ( 20935630) Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		12 interactors: APH1A APPBP2 ATXN1 CBX1 CBX3 CLU HDAC1 MAPK1 SIN3A TIMM13 TXNDC9 YWHAZ	29 interactors: ABI3BP ARL5A C11orf30 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EHMT2 HIST1H1E HIST1H3A HIST1H3C HIST3H3 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN
Entrez ID		8462	10951
HPRD ID		04488	05149
Ensembl ID		ENSG00000172059	ENSG00000108468
Uniprot IDs		B7ZAX4 O14901 Q53QU8	P83916 Q6IBN6
PDB IDs		1PO4	2FMM 3F2U 3Q6S
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cellular Localization Platelet Activation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Protein Localization Neurotrophin Signaling Pathway Establishment Of Localization In Cell Negative Regulation Of Cellular Metabolic Process Cytoplasmic Transport Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Protein Localization Protein Transport Protein Targeting To Mitochondrion Rhythmic Process Regulation Of Apoptotic Process Establishment Of Protein Localization Histone Deacetylation Protein Localization To Mitochondrion Protein Deacetylation Positive Regulation Of Tau-protein Kinase Activity Regulation Of Neuronal Signal Transduction Response To Methylglyoxal Microglial Cell Proliferation Negative Regulation Of Histone H3-K27 Acetylation Intracellular Transport Regulation Of Cell Death Establishment Of Protein Localization To Organelle Apoptotic Signaling Pathway Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Biosynthetic Process Intracellular Protein Transport Negative Regulation Of Apoptotic Process Mitochondrion Organization Negative Regulation Of Programmed Cell Death MAPK Import Into Nucleus Positive Regulation Of Neurofibrillary Tangle Assembly Apoptotic Process Protein Targeting Negative Regulation Of Cell Death Programmed Cell Death Cell Death Death	DNA Methylation On Cytosine Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of RNA Metabolic Process Chromatin Silencing Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification DNA Metabolic Process Gene Silencing Regulation Of Gene Expression DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Methylation Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Organelle Organization Regulation Of Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Silencing At RDNA RNA Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle S-adenosylmethioninamine Metabolic Process RNA Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Nucleosome Assembly DNA Methylation Involved In Embryo Development S-adenosylhomocysteine Metabolic Process Chromatin Assembly Cellular Macromolecule Biosynthetic Process Nucleosome Organization
Tagcloud ?		adenovirus adhesion augments coding constitutes ec ecs emerging exhibit inhibits interfering knockdown kruppel leukocyte lipopolysaccharide maturity mechanistically mellitus mody7 necrosis neonatal organism p65 potently proinflammatory promoters selectin uncovered vascular	apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils
Tagcloud (Difference) ?		adenovirus adhesion augments coding constitutes ec ecs emerging exhibit inhibits interfering knockdown kruppel leukocyte lipopolysaccharide maturity mechanistically mellitus mody7 necrosis neonatal organism p65 potently proinflammatory promoters selectin uncovered vascular	apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils
Tagcloud (Intersection) ?