TPST1 and CCR8

Number of citations of the paper that reports this interaction (PMID 17558413)
13

Data Source:
HPRD (in vitro)

		TPST1	CCR8
Gene Name		tyrosylprotein sulfotransferase 1	chemokine (C-C motif) receptor 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein-tyrosine Sulfotransferase Activity	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity
	Biological Process	Peptidyl-tyrosine Sulfation Inflammatory Response	Chemotaxis Immune Response Cell Adhesion G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG	6 interactors: CCL1 CCL16 CCL17 CCL4 TPST1 TPST2
Entrez ID		8460	1237
HPRD ID		07216	03497
Ensembl ID		ENSG00000169902	ENSG00000179934
Uniprot IDs		O60507	P51685
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cell Adhesion Locomotion Positive Regulation Of Leukocyte Chemotaxis Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Migration Cell Surface Receptor Signaling Pathway Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Response To Wounding Cellular Response To Stimulus Leukocyte Adhesive Activation Regulation Of Chemotaxis Cellular Response To Organic Substance G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Immune System Process Regulation Of Behavior Leukocyte Migration Response To Organic Substance Response To Stimulus Positive Regulation Of Macrophage Chemotaxis Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Signal Transduction Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Immune Response Positive Regulation Of Cell Motility Thrombin Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Leukocyte Tethering Or Rolling Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Signaling Cell Communication Blood Coagulation, Intrinsic Pathway Cellular Metal Ion Homeostasis Blood Coagulation Hemostasis Cellular Cation Homeostasis Negative Regulation Of Interleukin-12 Production	Cell Chemotaxis Peptidyl-tyrosine Sulfation Protein Sulfation Inflammatory Response Sulfation Chemotaxis Cell Migration Cell Motility Locomotion Immune Response Defense Response Movement Of Cell Or Subcellular Component Response To External Stimulus Prevention Of Polyspermy Immune System Process Cell-cell Signaling Positive Regulation Of Natural Killer Cell Chemotaxis Negative Regulation By Host Of Viral Transcription Sulfur Compound Metabolic Process Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Egg Activation Response To Stress Negative Regulation Of Viral Transcription Negative Regulation Of Myoblast Differentiation Positive Regulation Of Calcium-mediated Signaling Positive Chemotaxis Regulation Of Lymphocyte Migration Interaction With Symbiont Regulation Of Myoblast Differentiation Regulation Of Calcium-mediated Signaling Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Leukocyte Chemotaxis
Tagcloud ?			3p21 bimodal call chemokine chemokines chemotaxis chemr1 ckr cloning cxcr1 cxcr4 faint freshly l1 leukocytes lymphocytes mobilization nomenclature phytohemagglutinin responsiveness served stably stromal subnanomolar ter1 termed transfected unusual
Tagcloud (Difference) ?			3p21 bimodal call chemokine chemokines chemotaxis chemr1 ckr cloning cxcr1 cxcr4 faint freshly l1 leukocytes lymphocytes mobilization nomenclature phytohemagglutinin responsiveness served stably stromal subnanomolar ter1 termed transfected unusual
Tagcloud (Intersection) ?