CCR8 and CCL16

Number of citations of the paper that reports this interaction (PubMedID 10910894)
0

Data Source:
HPRD (in vitro, in vivo)

		CCR8	CCL16
Description		C-C motif chemokine receptor 8	C-C motif chemokine ligand 16
Image
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane	Extracellular Region Extracellular Space
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding	Cytokine Activity Protein Binding Chemokine Activity Chemoattractant Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus	Chemotaxis Inflammatory Response Immune Response Cell Communication Cell-cell Signaling Positive Regulation Of Cell Migration Eosinophil Chemotaxis Positive Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)	Initial pursuit acceleration ( 29064472)
Interacting Genes		19 interacting genes: ATP2A1 CCL1 CCL16 CCL17 CCL4 EI24 ERGIC3 GABBR1 GABRD NAGPA PAQR6 PLEKHB1 RTN3 SPNS1 SPP1 THY1 TPST1 TPST2 UCKL1	6 interacting genes: CCL5 CCR1 CCR5 CCR8 HRH4 UBQLN2
Entrez ID		1237	6360
HPRD ID		03497	03233
Ensembl ID		ENSG00000179934	ENSG00000275152
Uniprot IDs		P51685	O15467
PDB IDs		8KFX 8KFY 8KFZ 8TLM 8U1U 8XML	5LTL 7SCT 8FK9
Enriched GO Terms of Interacting Partners?		Chemokine Activity Eosinophil Migration Eosinophil Chemotaxis Protein-tyrosine Sulfotransferase Activity Cytokine Activity CCR Chemokine Receptor Binding Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell-cell Signaling Signaling Cell Communication Axolemma Cell Chemotaxis Chemokine-mediated Signaling Pathway Granulocyte Chemotaxis Negative Regulation Of Neuron Projection Regeneration 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Granulocyte Migration Positive Regulation Of Calcium Ion Transport Humoral Immune Response Positive Regulation Of Transport Golgi Apparatus Gamma-aminobutyric Acid Signaling Pathway Myeloid Leukocyte Migration Chemotaxis Leukocyte Chemotaxis Regulation Of Neuron Projection Regeneration Locomotion Positive Regulation Of Leukocyte Migration Synaptic Transmission, GABAergic Extracellular Space Maintenance Of Mitochondrion Location Regulation Of Transport Positive Regulation Of Monoatomic Ion Transport Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Peptidyl-tyrosine Sulfation N-acetylglucosamine-1-phosphodiester Alpha-N-acetylglucosaminidase Activity Calcium-dependent ATPase Activity Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Signal Transduction Relaxation Of Skeletal Muscle H Zone Regulation Of Calcium Ion Transport Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction G Protein-coupled Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential G Protein-coupled GABA Receptor Activity G Protein-coupled Receptor Dimeric Complex	Chemokine Receptor Activity Chemokine-mediated Signaling Pathway Dendritic Cell Migration Dendritic Cell Chemotaxis C-C Chemokine Binding C-C Chemokine Receptor Activity Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Chemokine (C-C Motif) Ligand 5 Binding Positive Regulation Of Cytosolic Calcium Ion Concentration Cytokine-mediated Signaling Pathway Cell Chemotaxis Response To Cytokine Response To Peptide Negative Regulation Of Macrophage Apoptotic Process Chemotaxis Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Locomotion G Protein-coupled Receptor Activity Cellular Response To Cytokine Stimulus Leukocyte Chemotaxis Positive Regulation Of Neuroinflammatory Response Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Monocyte Chemotaxis Monocyte Chemotaxis Calcium-mediated Signaling Inflammatory Response Regulation Of Monocyte Chemotaxis Regulation Of Myeloid Cell Apoptotic Process Immune Response Cell-cell Signaling Leukocyte Migration Regulation Of Neuroinflammatory Response Signaling Calcium Ion Transport Cell Communication Negative Regulation Of Viral Genome Replication Defense Response G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Leukocyte Apoptotic Process Coreceptor Activity Chemokine Receptor Antagonist Activity Chemokine (C-C Motif) Ligand 5 Signaling Pathway CCR4 Chemokine Receptor Binding Intracellular Signaling Cassette External Side Of Plasma Membrane Negative Regulation Of Viral Process Regulation Of Viral Genome Replication Cell Migration Chemokine (C-C Motif) Ligand 7 Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?