TPST1 and CMKLR1

Number of citations of the paper that reports this interaction (PMID 17558413)
13

Data Source:
HPRD (in vitro)

		TPST1	CMKLR1
Gene Name		tyrosylprotein sulfotransferase 1	chemokine-like receptor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein-tyrosine Sulfotransferase Activity	Receptor Activity G-protein Coupled Receptor Activity Chemokine Receptor Activity Protein Binding
	Biological Process	Peptidyl-tyrosine Sulfation Inflammatory Response	Skeletal System Development Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Macrophage Chemotaxis Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-12 Production Positive Regulation Of Fat Cell Differentiation Regulation Of Calcium-mediated Signaling Chemokine-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 22688191) Erectile dysfunction and prostate cancer treatment ( 20932654) Response to platinum-based chemotherapy in non-small-cell lung cancer ( 21483023)
Protein-Protein Interactions		6 interactors: CCR1 CCR8 CMKLR1 GP1BA GPR1 SELPLG	2 interactors: TPST1 TPST2
Entrez ID		8460	1240
HPRD ID		07216	03829
Ensembl ID		ENSG00000169902	ENSG00000174600
Uniprot IDs		O60507	Q99788
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway G-protein Coupled Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Response To Cytokine Cell Adhesion Locomotion Positive Regulation Of Leukocyte Chemotaxis Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Migration Cell Surface Receptor Signaling Pathway Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Behavior Response To Wounding Cellular Response To Stimulus Leukocyte Adhesive Activation Regulation Of Chemotaxis Cellular Response To Organic Substance G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Immune System Process Regulation Of Behavior Leukocyte Migration Response To Organic Substance Response To Stimulus Positive Regulation Of Macrophage Chemotaxis Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Signal Transduction Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Migration Immune Response Positive Regulation Of Cell Motility Thrombin Receptor Signaling Pathway Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Leukocyte Tethering Or Rolling Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Dendritic Cell Chemotaxis Signaling Cell Communication Blood Coagulation, Intrinsic Pathway Cellular Metal Ion Homeostasis Blood Coagulation Hemostasis Cellular Cation Homeostasis Negative Regulation Of Interleukin-12 Production	Peptidyl-tyrosine Sulfation Protein Sulfation Sulfation Sulfur Compound Metabolic Process Prevention Of Polyspermy Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Egg Activation Peptidyl-amino Acid Modification Membrane Fusion Single Fertilization Fertilization Cellular Protein Modification Process
Tagcloud ?			12q24 appendix array broad chemokine chromosome cloning encodes encoding fetal fluorescence formyl hematopoietic homology hybridization localized lymph marrow node notable nucleotide sequence seven situ spleen structural thymus transmembrane
Tagcloud (Difference) ?			12q24 appendix array broad chemokine chromosome cloning encodes encoding fetal fluorescence formyl hematopoietic homology hybridization localized lymph marrow node notable nucleotide sequence seven situ spleen structural thymus transmembrane
Tagcloud (Intersection) ?