ATRN and ZNF408

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
BioGRID (two hybrid)

		ATRN	ZNF408
Description		attractin	zinc finger protein 408
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Membrane Extracellular Exosome	Nucleus
	Molecular Function	Carbohydrate Binding Signaling Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Inflammatory Response Cerebellum Development Regulation Of Multicellular Organism Growth Myelination Pigmentation	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Asthma ( 29273806) Diisocyanate-induced asthma ( 25918132) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Monocyte count ( 32888494) Night sleep phenotypes ( 27126917) Postcentral gyrus volume ( 31530798) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)	Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)
Interacting Genes		4 interacting genes: COPS5 DYRK1A XRN2 ZNF408	83 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1
Entrez ID		8455	79797
HPRD ID		04388	18338
Ensembl ID		ENSG00000088812	ENSG00000175213
Uniprot IDs		B4DZ36 O75882	B4DXY4 Q9H9D4
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Coactivator Activity Negative Regulation Of Heterochromatin Formation Regulation Of Neurofibrillary Tangle Assembly Splicing Factor Binding Histone H3T45 Kinase Activity Exosomal Secretion Macrophage Migration Inhibitory Factor Binding DeNEDDylase Activity Transcription Termination Site Sequence-specific DNA Binding Termination Of RNA Polymerase II Transcription 5'-3' RNA Exonuclease Activity RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Neurofilament Regulation Of Heterochromatin Formation Protein Deneddylation 5'-3' Exonuclease Activity Metal-dependent Deubiquitinase Activity Negative Regulation Of Microtubule Polymerization Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Eukaryotic Translation Initiation Factor 3 Complex Tau-protein Kinase Activity Regulation Of Cellular Response To Stress Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Chromatin Organization Regulation Of Gene Expression Regulation Of Inclusion Body Assembly Identical Protein Binding Regulation Of Protein Neddylation Regulation Of IRE1-mediated Unfolded Protein Response Protein Neddylation DNA-templated Transcription Termination Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Splicing Protein Serine/threonine/tyrosine Kinase Activity	Identical Protein Binding Nucleus Protein Binding Zinc Ion Binding Intermediate Filament Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex MRNA Processing Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process RNA Processing Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Muramyl Dipeptide
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